Induced Hematopoietic Stem Cells: Unlocking Restrictions in Lineage Potential and Self-renewal.

Martin Wahlestedt; David Bryder

doi:10.1016/j.stem.2014.04.008

Induced Hematopoietic Stem Cells: Unlocking Restrictions in Lineage Potential and Self-renewal.

Martin Wahlestedt, David Bryder

Research output: Contribution to journal › Debate/Note/Editorial › peer-review

Abstract

Obtaining sufficient numbers of immunologically matched hematopoietic stem cells (HSCs) poses a major clinical hurdle in bone marrow transplantation therapies. In a recent study in Cell, Riddell et al. (2014) generate induced HSCs from differentiated blood cells, which may serve as a potential solution to this clinical challenge.

Original language	English
Pages (from-to)	555-556
Journal	Cell Stem Cell
Volume	14
Issue number	5
DOIs	https://doi.org/10.1016/j.stem.2014.04.008
Publication status	Published - 2014

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Stem Cell Aging (013212073)

Subject classification (UKÄ)

Cell Biology

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10.1016/j.stem.2014.04.008

http://www.ncbi.nlm.nih.gov/pubmed/24792111?dopt=Abstract

Cite this

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title = "Induced Hematopoietic Stem Cells: Unlocking Restrictions in Lineage Potential and Self-renewal.",

abstract = "Obtaining sufficient numbers of immunologically matched hematopoietic stem cells (HSCs) poses a major clinical hurdle in bone marrow transplantation therapies. In a recent study in Cell, Riddell et al. (2014) generate induced HSCs from differentiated blood cells, which may serve as a potential solution to this clinical challenge.",

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AB - Obtaining sufficient numbers of immunologically matched hematopoietic stem cells (HSCs) poses a major clinical hurdle in bone marrow transplantation therapies. In a recent study in Cell, Riddell et al. (2014) generate induced HSCs from differentiated blood cells, which may serve as a potential solution to this clinical challenge.

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Induced Hematopoietic Stem Cells: Unlocking Restrictions in Lineage Potential and Self-renewal.

Abstract

Bibliographical note

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