Inertia induced breakdown of acoustic sorting efficiency at high flow rates

Eva Undvall, Fabio Garofalo, Giuseppe Procopio, Andreas Lenshof, Thomas Laurell, Thierry Baasch

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

Abstract

We investigated the impact of inertial forces on acoustic sorting at high sample throughputs. Above a critical flow rate, we observed an unexpected inertia induced breakdown of the sorting efficiency that is not due to the wall induced lift force and was not previously described in the literature. We analyzed the effect experimentally and theoretically, providing an explanation to the phenomena, and suggest conditions to maximize the sample throughput, while keeping the sorting efficiency intact. The observed phenomena is generic to all separation techniques that rely on field based (electrical, magnetic, acoustic) forces acting on cells/particles.

Original languageEnglish
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages895-896
Number of pages2
ISBN (Electronic)9781733419031
Publication statusPublished - 2021
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
Duration: 2021 Oct 102021 Oct 14

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/TerritoryUnited States
CityPalm Springs, Virtual
Period2021/10/102021/10/14

Subject classification (UKÄ)

  • Fluid Mechanics and Acoustics

Keywords

  • Acoustic particle manipulation
  • Fluid mechanics
  • High throughput
  • Inertia
  • Microfluidic sorting

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