Abstract
Urothelial carcinoma (UC) aggressiveness is determined by tumor inherent molecular characteristics, such as molecular subtypes, as well as by host reactions directed toward the tumor. Cell types responsible for the host׳s response include tumor-infiltrating lymphocytes (TILs) and tumor-associated macrophages (TAMs). The aim of the present investigation was to explore the immunological response in relation to UC molecular subtypes and to evaluate the prognostic effect of TIL and TAM counts in tissue sections from muscle-invasive (MI) tumors.
Original language | English |
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Pages (from-to) | 791-797 |
Journal | Urologic Oncology |
Volume | 32 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2014 |
Subject classification (UKÄ)
- Urology and Nephrology
- Cancer and Oncology