Inhibition of kainic acid binding to glutamate receptors by extracts of Gastrodia

Maria Andersson, Ola Bergendorff, Mogens Nielsen, Olov Sterner, Robin Witt, Jinglu Ai, Aiping Lu, An Min Wang

Research output: Contribution to journalArticlepeer-review

Abstract

S-(4-hydroxybenzyl)glutathione was isolated as the major principle responsible for the inhibition of the in vitro binding of kainic acid to brain glutamate receptors by water extracts of the plant Gastrodia elata. The affinity (IC50 value) of the compound is slightly lower compared to glutamate and glutathione.
Original languageEnglish
Pages (from-to)835-836
JournalPhytochemistry
Volume38
Issue number4
DOIs
Publication statusPublished - 1995

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Department of Dermatology and Venereology (Lund) (013006000), Organic chemistry (S/LTH) (011001240)

Subject classification (UKÄ)

  • Dermatology and Venereal Diseases

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