Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level

S. H. Kim; M. Antfolk; L. Jonsson; K. Saori; S. Kaneda; T. Fujii; T. Laurell

Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level

S. H. Kim, M. Antfolk, L. Jonsson, K. Saori, S. Kaneda, T. Fujii, T. Laurell

Research output: Chapter in Book/Report/Conference proceeding › Paper in conference proceeding › peer-review

Abstract

We present an advanced approach for single-cell analysis of circulating tumor cells (CTCs) by integrating an acoustofluidic chip for sample preparation, including simultaneous acoustophoretic separation and enrichment of the separated cells, onto an electroactive microwell array (EMA) for single-cell arraying. The integrated device shows highly efficient cell recovery of target cells (82.5%) and depletion of non-target cells (92.8%).

Original language	English
Title of host publication	MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	346-348
Number of pages	3
ISBN (Electronic)	9780979806483
Publication status	Published - 2015
Event	19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 - Gyeongju, Korea, Republic of Duration: 2015 Oct 25 → 2015 Oct 29

Conference

Conference	19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015
Country/Territory	Korea, Republic of
City	Gyeongju
Period	2015/10/25 → 2015/10/29

Subject classification (UKÄ)

Biomedical Laboratory Science/Technology

Free keywords

Acoustophoresis
Circulating tumor cells
Dielectrophoresis

Cite this

Kim, S. H., Antfolk, M., Jonsson, L., Saori, K., Kaneda, S., Fujii, T., & Laurell, T. (2015). Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level. In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 346-348). Chemical and Biological Microsystems Society.

Kim, S. H. ; Antfolk, M. ; Jonsson, L. et al. / Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level. MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2015. pp. 346-348

@inproceedings{0bf6403931274988ae84ad43aedcacbd,

title = "Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level",

abstract = "We present an advanced approach for single-cell analysis of circulating tumor cells (CTCs) by integrating an acoustofluidic chip for sample preparation, including simultaneous acoustophoretic separation and enrichment of the separated cells, onto an electroactive microwell array (EMA) for single-cell arraying. The integrated device shows highly efficient cell recovery of target cells (82.5%) and depletion of non-target cells (92.8%).",

keywords = "Acoustophoresis, Circulating tumor cells, Dielectrophoresis",

author = "Kim, {S. H.} and M. Antfolk and L. Jonsson and K. Saori and S. Kaneda and T. Fujii and T. Laurell",

year = "2015",

language = "English",

pages = "346--348",

booktitle = "MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Chemical and Biological Microsystems Society",

note = "19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015 ; Conference date: 25-10-2015 Through 29-10-2015",

}

Kim, SH, Antfolk, M, Jonsson, L, Saori, K, Kaneda, S, Fujii, T & Laurell, T 2015, Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level. in MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, pp. 346-348, 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015, Gyeongju, Korea, Republic of, 2015/10/25.

Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level. / Kim, S. H.; Antfolk, M.; Jonsson, L. et al.
MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2015. p. 346-348.

Research output: Chapter in Book/Report/Conference proceeding › Paper in conference proceeding › peer-review

TY - GEN

T1 - Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level

AU - Kim, S. H.

AU - Antfolk, M.

AU - Jonsson, L.

AU - Saori, K.

AU - Kaneda, S.

AU - Fujii, T.

AU - Laurell, T.

PY - 2015

Y1 - 2015

N2 - We present an advanced approach for single-cell analysis of circulating tumor cells (CTCs) by integrating an acoustofluidic chip for sample preparation, including simultaneous acoustophoretic separation and enrichment of the separated cells, onto an electroactive microwell array (EMA) for single-cell arraying. The integrated device shows highly efficient cell recovery of target cells (82.5%) and depletion of non-target cells (92.8%).

AB - We present an advanced approach for single-cell analysis of circulating tumor cells (CTCs) by integrating an acoustofluidic chip for sample preparation, including simultaneous acoustophoretic separation and enrichment of the separated cells, onto an electroactive microwell array (EMA) for single-cell arraying. The integrated device shows highly efficient cell recovery of target cells (82.5%) and depletion of non-target cells (92.8%).

KW - Acoustophoresis

KW - Circulating tumor cells

KW - Dielectrophoresis

UR - http://www.scopus.com/inward/record.url?scp=84983365292&partnerID=8YFLogxK

M3 - Paper in conference proceeding

AN - SCOPUS:84983365292

SP - 346

EP - 348

BT - MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Chemical and Biological Microsystems Society

T2 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2015

Y2 - 25 October 2015 through 29 October 2015

ER -

Kim SH, Antfolk M, Jonsson L, Saori K, Kaneda S, Fujii T et al. Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level. In MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2015. p. 346-348

Integration of acousto- and dielectrophoresis allows tumor cell separation and enrichment followed by arraying of target cells toward analysis of circulating tumor cells at the single-cell level

Abstract

Conference

Subject classification (UKÄ)

Free keywords

Other files and links

Fingerprint

Cite this