Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.

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Abstract

Urothelial carcinoma of the bladder (UC) is a common malignancy. Although extensive transcriptome analysis has provided insights into the gene expression patterns of this tumor type, the mechanistic underpinnings of differential methylation remain poorly understood. Multi-level genomic data may be used to profile the regulatory potential and landscape of differential methylation in cancer and gain understanding of the processes underlying epigenetic and phenotypic characteristics of tumors.
Original languageEnglish
Article number23
JournalGenome Medicine
Volume7
Issue number1
DOIs
Publication statusPublished - 2015

Subject classification (UKÄ)

  • Cancer and Oncology

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