Intensified Tuberculosis Case-Finding in HIV-Positive Adults Managed at Ethiopian Health Centers: Diagnostic Yield of Xpert MTB/RIF Compared with Smear Microscopy and Liquid Culture.

Taye Balcha, Erik Sturegård, Niclas Winqvist, Sten Skogmar, Anton Reepalu, Zelalem Habtamu Jemal, Gudeta Tibesso, Thomas Schön, Per Björkman

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Abstract

Detection of active tuberculosis (TB) before antiretroviral therapy (ART) initiation is important, but optimal diagnostic methods for use in resource-limited settings are lacking. We assessed the prevalence of TB, evaluated the diagnostic yield of Xpert MTB/RIF in comparison with smear microscopy and culture, and the impact of Xpert results on clinical management in HIV-positive adults eligible for ART at health centers in a region of Ethiopia.
Original languageEnglish
Article numbere85478
JournalPLoS ONE
Volume9
Issue number1
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Microbiology in the medical area
  • Infectious Medicine

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