Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma

Laura Toussaint; Petter Brandal; Anna Embring; Jacob Engellau; Morten Egeberg Evensen; Romualdas Griskeviskius; Jolanta Hansen; Henna Hietala; Gun Wickart Johansson; Morten Jørgensen; Paul Heinz Kramer; Ingrid Kristensen; Kaisa Lehtio; Henriette Magelssen; Maja Vestmø Maraldo; Kirsten Marienhagen; Ulla Martinsson; Kristina Nilsson; Sarah Peters; Sandija Plaude; Klaus Seiersen; Daiva Sendiuliene; Bob Smulders; Tone Edvardsen; Johan Martin Søbstad; Zarah Taheri; Leila Vaalavirta; Anne Vestergaard; Beate Timmermann; Yasmin Lassen-Ramshad; NOPHO Radiotherapy Working Group

doi:10.1080/0284186X.2021.2022202

Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma

Laura Toussaint, Petter Brandal, Anna Embring, Jacob Engellau, Morten Egeberg Evensen, Romualdas Griskeviskius, Jolanta Hansen, Henna Hietala, Gun Wickart Johansson, Morten Jørgensen, Paul Heinz Kramer, Ingrid Kristensen, Kaisa Lehtio, Henriette Magelssen, Maja Vestmø Maraldo, Kirsten Marienhagen, Ulla Martinsson, Kristina Nilsson, Sarah Peters, Sandija PlaudeKlaus Seiersen, Daiva Sendiuliene, Bob Smulders, Tone Edvardsen, Johan Martin Søbstad, Zarah Taheri, Leila Vaalavirta, Anne Vestergaard, Beate Timmermann, Yasmin Lassen-Ramshad, NOPHO Radiotherapy Working Group

Research output: Contribution to journal › Letter › peer-review

Abstract

Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in target delineation and treatment plans for these tumours.

Original language	English
Pages (from-to)	235-238
Number of pages	4
Journal	Acta Oncologica
Volume	61
Issue number	2
DOIs	https://doi.org/10.1080/0284186X.2021.2022202
Publication status	Published - 2022

Subject classification (UKÄ)

Cancer and Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1080/0284186X.2021.2022202

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Toussaint, L., Brandal, P., Embring, A., Engellau, J., Evensen, M. E., Griskeviskius, R., Hansen, J., Hietala, H., Wickart Johansson, G., Jørgensen, M., Kramer, P. H., Kristensen, I., Lehtio, K., Magelssen, H., Maraldo, M. V., Marienhagen, K., Martinsson, U., Nilsson, K., Peters, S., ... NOPHO Radiotherapy Working Group (2022). Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma. Acta Oncologica, 61(2), 235-238. https://doi.org/10.1080/0284186X.2021.2022202

@article{d2e822479f7b416f8fb1abbd685e8c24,

title = "Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma",

abstract = "Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in target delineation and treatment plans for these tumours.",

author = "Laura Toussaint and Petter Brandal and Anna Embring and Jacob Engellau and Evensen, {Morten Egeberg} and Romualdas Griskeviskius and Jolanta Hansen and Henna Hietala and {Wickart Johansson}, Gun and Morten J{\o}rgensen and Kramer, {Paul Heinz} and Ingrid Kristensen and Kaisa Lehtio and Henriette Magelssen and Maraldo, {Maja Vestm{\o}} and Kirsten Marienhagen and Ulla Martinsson and Kristina Nilsson and Sarah Peters and Sandija Plaude and Klaus Seiersen and Daiva Sendiuliene and Bob Smulders and Tone Edvardsen and S{\o}bstad, {Johan Martin} and Zarah Taheri and Leila Vaalavirta and Anne Vestergaard and Beate Timmermann and Yasmin Lassen-Ramshad and {NOPHO Radiotherapy Working Group}",

year = "2022",

doi = "10.1080/0284186X.2021.2022202",

language = "English",

volume = "61",

pages = "235--238",

journal = "Acta Oncologica",

issn = "0284-186X",

publisher = "Taylor & Francis",

number = "2",

}

Toussaint, L, Brandal, P, Embring, A, Engellau, J, Evensen, ME, Griskeviskius, R, Hansen, J, Hietala, H, Wickart Johansson, G, Jørgensen, M, Kramer, PH, Kristensen, I, Lehtio, K, Magelssen, H, Maraldo, MV, Marienhagen, K, Martinsson, U, Nilsson, K, Peters, S, Plaude, S, Seiersen, K, Sendiuliene, D, Smulders, B, Edvardsen, T, Søbstad, JM, Taheri, Z, Vaalavirta, L, Vestergaard, A, Timmermann, B, Lassen-Ramshad, Y & NOPHO Radiotherapy Working Group 2022, 'Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma', Acta Oncologica, vol. 61, no. 2, pp. 235-238. https://doi.org/10.1080/0284186X.2021.2022202

TY - JOUR

T1 - Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma

AU - Toussaint, Laura

AU - Brandal, Petter

AU - Embring, Anna

AU - Engellau, Jacob

AU - Evensen, Morten Egeberg

AU - Griskeviskius, Romualdas

AU - Hansen, Jolanta

AU - Hietala, Henna

AU - Wickart Johansson, Gun

AU - Jørgensen, Morten

AU - Kramer, Paul Heinz

AU - Kristensen, Ingrid

AU - Lehtio, Kaisa

AU - Magelssen, Henriette

AU - Maraldo, Maja Vestmø

AU - Marienhagen, Kirsten

AU - Martinsson, Ulla

AU - Nilsson, Kristina

AU - Peters, Sarah

AU - Plaude, Sandija

AU - Seiersen, Klaus

AU - Sendiuliene, Daiva

AU - Smulders, Bob

AU - Edvardsen, Tone

AU - Søbstad, Johan Martin

AU - Taheri, Zarah

AU - Vaalavirta, Leila

AU - Vestergaard, Anne

AU - Timmermann, Beate

AU - Lassen-Ramshad, Yasmin

AU - NOPHO Radiotherapy Working Group

PY - 2022

Y1 - 2022

N2 - Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in target delineation and treatment plans for these tumours.

AB - Postoperative radiotherapy for intracranial paediatric ependymoma is challenging both for target definition and treatment planning [1]. Delineation of the tumour bed is difficult, as structures in prior contact with the tumour will shift back into their original positions after surgery. In infratentorial cases, the target is adjacent to the brainstem and upper spinal cord, therefore the relatively high prescription dose and sparing of surrounding organs at risk (OARs) need to be balanced. Through the radiotherapy working-group of the Nordic Organization of Pediatric Hematology and Oncology (NOPHO) and in collaboration with the Westdeutsches Protonentherapizentrum Essen (WPE), a study was performed to quantify inter-centre variations in target delineation and treatment plans for these tumours.

U2 - 10.1080/0284186X.2021.2022202

DO - 10.1080/0284186X.2021.2022202

M3 - Letter

C2 - 34970940

AN - SCOPUS:85122663205

SN - 0284-186X

VL - 61

SP - 235

EP - 238

JO - Acta Oncologica

JF - Acta Oncologica

IS - 2

ER -

Inter-observer variation in target delineation and dose trade-off for radiotherapy of paediatric ependymoma

Abstract

Subject classification (UKÄ)

UN SDGs

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Cite this