Investigation and analysis of ferrous sulfate polyvinyl alcohol (PVA) gel dosimeter

Brendan Hill; Sven Bäck; Martin Lepage; John Simpson; Brendan Healy; Clive Baldock

doi:10.1088/0031-9155/47/23/309

Investigation and analysis of ferrous sulfate polyvinyl alcohol (PVA) gel dosimeter

Brendan Hill, Sven Bäck, Martin Lepage, John Simpson, Brendan Healy, Clive Baldock

Medical Radiation Physics, Malmö

Research output: Contribution to journal › Article › peer-review

Abstract

Ferrous sulfate (Fe(SO4)2) PVA gels were investigated for a range of absorbed doses up to 20 Gy using both magnetic resonance imaging (MRI) and spectrophotometry to determine R1 and optical density (OD) dose responses and G values. It was found that R1- and OD-dose sensitivities increased with O2 saturation or by the introduction of a freeze-thaw cycle during preparation of the PVA gel. The storage temperature of the Fe(SO4)2 PVA gel at -18 degrees C increased R1-dose sensitivity above that of gels stored at 5 degrees C. The addition of sucrose to the formulation was found to result in the largest increase in both R1- and OD-dose sensitivities. Fe(SO4)2 PVA gel with and without the addition of xylenol orange was demonstrated to have a G value of approximately 20 ions/100 eV and with sucrose approximately 24 ions/100 eV.

Original language	English
Pages (from-to)	4233-4246
Journal	Physics in Medicine and Biology
Volume	47
Issue number	23
DOIs	https://doi.org/10.1088/0031-9155/47/23/309
Publication status	Published - 2002

Subject classification (UKÄ)

Radiology and Medical Imaging

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10.1088/0031-9155/47/23/309

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title = "Investigation and analysis of ferrous sulfate polyvinyl alcohol (PVA) gel dosimeter",

abstract = "Ferrous sulfate (Fe(SO4)2) PVA gels were investigated for a range of absorbed doses up to 20 Gy using both magnetic resonance imaging (MRI) and spectrophotometry to determine R1 and optical density (OD) dose responses and G values. It was found that R1- and OD-dose sensitivities increased with O2 saturation or by the introduction of a freeze-thaw cycle during preparation of the PVA gel. The storage temperature of the Fe(SO4)2 PVA gel at -18 degrees C increased R1-dose sensitivity above that of gels stored at 5 degrees C. The addition of sucrose to the formulation was found to result in the largest increase in both R1- and OD-dose sensitivities. Fe(SO4)2 PVA gel with and without the addition of xylenol orange was demonstrated to have a G value of approximately 20 ions/100 eV and with sucrose approximately 24 ions/100 eV.",

author = "Brendan Hill and Sven B{\"a}ck and Martin Lepage and John Simpson and Brendan Healy and Clive Baldock",

year = "2002",

doi = "10.1088/0031-9155/47/23/309",

language = "English",

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pages = "4233--4246",

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TY - JOUR

T1 - Investigation and analysis of ferrous sulfate polyvinyl alcohol (PVA) gel dosimeter

AU - Hill, Brendan

AU - Bäck, Sven

AU - Lepage, Martin

AU - Simpson, John

AU - Healy, Brendan

AU - Baldock, Clive

PY - 2002

Y1 - 2002

N2 - Ferrous sulfate (Fe(SO4)2) PVA gels were investigated for a range of absorbed doses up to 20 Gy using both magnetic resonance imaging (MRI) and spectrophotometry to determine R1 and optical density (OD) dose responses and G values. It was found that R1- and OD-dose sensitivities increased with O2 saturation or by the introduction of a freeze-thaw cycle during preparation of the PVA gel. The storage temperature of the Fe(SO4)2 PVA gel at -18 degrees C increased R1-dose sensitivity above that of gels stored at 5 degrees C. The addition of sucrose to the formulation was found to result in the largest increase in both R1- and OD-dose sensitivities. Fe(SO4)2 PVA gel with and without the addition of xylenol orange was demonstrated to have a G value of approximately 20 ions/100 eV and with sucrose approximately 24 ions/100 eV.

AB - Ferrous sulfate (Fe(SO4)2) PVA gels were investigated for a range of absorbed doses up to 20 Gy using both magnetic resonance imaging (MRI) and spectrophotometry to determine R1 and optical density (OD) dose responses and G values. It was found that R1- and OD-dose sensitivities increased with O2 saturation or by the introduction of a freeze-thaw cycle during preparation of the PVA gel. The storage temperature of the Fe(SO4)2 PVA gel at -18 degrees C increased R1-dose sensitivity above that of gels stored at 5 degrees C. The addition of sucrose to the formulation was found to result in the largest increase in both R1- and OD-dose sensitivities. Fe(SO4)2 PVA gel with and without the addition of xylenol orange was demonstrated to have a G value of approximately 20 ions/100 eV and with sucrose approximately 24 ions/100 eV.

U2 - 10.1088/0031-9155/47/23/309

DO - 10.1088/0031-9155/47/23/309

M3 - Article

SN - 1361-6560

VL - 47

SP - 4233

EP - 4246

JO - Physics in Medicine and Biology

JF - Physics in Medicine and Biology

IS - 23

ER -

Investigation and analysis of ferrous sulfate polyvinyl alcohol (PVA) gel dosimeter

Abstract

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