Is craniofacial dysmorpholgy correlated with structural brain anomalies in schizophrenia?

BD Kelly, Thomas McNeil, A Lane, Karin Henriksson, A Kinsella, I Agartz

Research output: Contribution to journalArticlepeer-review

6 Citations (SciVal)

Abstract

This study aimed to examine the relationship between craniofacial dysmorphology and anomalies of brain morphology in schizophrenia. Assessments of craniofacial dysmorphology and magnetic resonance imaging of brain were performed independently of each other and blind to each other in 24 males with schizophrenia and 16 male controls. Ventricular cerebrospinal fluid volume was negatively correlated with total dysmorphology score in males with schizophrenia (i.e., the larger the ventricular cerebrospinal fluid volume, the lower the total dysmorphology score) but not in male controls. These findings suggest that craniofacial dysmorphology and anomalies of brain morphology may be associated with independent processes in the etiology of schizophrenia.
Original languageEnglish
Pages (from-to)349-355
JournalSchizophrenia Research
Volume80
Issue number2-3
DOIs
Publication statusPublished - 2005

Subject classification (UKÄ)

  • Psychiatry

Keywords

  • human
  • anthropometry
  • schizophrenia
  • magnetic resonance imaging
  • development
  • causality

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