Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.

Erik Björklund; Eva Lindberg; Malin Rundgren; Tobias Cronberg; Hans Friberg; Elisabet Englund

doi:10.1016/j.resuscitation.2013.11.022

Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.

Erik Björklund, Eva Lindberg, Malin Rundgren, Tobias Cronberg, Hans Friberg, Elisabet Englund

Research output: Contribution to journal › Article › peer-review

Abstract

Although well characterized in animals, brain damage in humans treated with hypothermia after cardiac arrest has not been systematically explored. In this study we aimed to describe the characteristic trait of selective eosinophilic neuronal death (SEND), and its correlation with time to return of spontaneous circulation (ROSC) in cardiac arrest patients who died after hypothermia treatment and were referred for autopsy.

Original language	English
Pages (from-to)	527-532
Journal	Resuscitation
Volume	85
Issue number	4
DOIs	https://doi.org/10.1016/j.resuscitation.2013.11.022
Publication status	Published - 2014

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Anaesthesiology and Intensive Care (013230022), Neurology, Lund (013027000), Pathology, (Lund) (013030000)

Subject classification (UKÄ)

Anesthesiology and Intensive Care

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10.1016/j.resuscitation.2013.11.022

http://www.ncbi.nlm.nih.gov/pubmed/24321320?dopt=Abstract

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title = "Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.",

abstract = "Although well characterized in animals, brain damage in humans treated with hypothermia after cardiac arrest has not been systematically explored. In this study we aimed to describe the characteristic trait of selective eosinophilic neuronal death (SEND), and its correlation with time to return of spontaneous circulation (ROSC) in cardiac arrest patients who died after hypothermia treatment and were referred for autopsy.",

author = "Erik Bj{\"o}rklund and Eva Lindberg and Malin Rundgren and Tobias Cronberg and Hans Friberg and Elisabet Englund",

note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Anaesthesiology and Intensive Care (013230022), Neurology, Lund (013027000), Pathology, (Lund) (013030000)",

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AU - Björklund, Erik

AU - Lindberg, Eva

AU - Rundgren, Malin

AU - Cronberg, Tobias

AU - Friberg, Hans

AU - Englund, Elisabet

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Anaesthesiology and Intensive Care (013230022), Neurology, Lund (013027000), Pathology, (Lund) (013030000)

PY - 2014

Y1 - 2014

N2 - Although well characterized in animals, brain damage in humans treated with hypothermia after cardiac arrest has not been systematically explored. In this study we aimed to describe the characteristic trait of selective eosinophilic neuronal death (SEND), and its correlation with time to return of spontaneous circulation (ROSC) in cardiac arrest patients who died after hypothermia treatment and were referred for autopsy.

AB - Although well characterized in animals, brain damage in humans treated with hypothermia after cardiac arrest has not been systematically explored. In this study we aimed to describe the characteristic trait of selective eosinophilic neuronal death (SEND), and its correlation with time to return of spontaneous circulation (ROSC) in cardiac arrest patients who died after hypothermia treatment and were referred for autopsy.

U2 - 10.1016/j.resuscitation.2013.11.022

DO - 10.1016/j.resuscitation.2013.11.022

M3 - Article

C2 - 24321320

SN - 1873-1570

VL - 85

SP - 527

EP - 532

JO - Resuscitation

JF - Resuscitation

IS - 4

ER -

Ischaemic brain damage after cardiac arrest and induced hypothermia-a systematic description of selective eosinophilic neuronal death. A neuropathologic study of 23 patients.

Abstract

Bibliographical note

Subject classification (UKÄ)

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