Kinetic preference for interaction of cisplatin with the G-C-rich wobble basepair region in both tRNA(Ala) and Mh(Ala)

Pal Papsai, Jasmin Aldag, Tina Persson, Sofi Elmroth

Research output: Contribution to journalArticlepeer-review

19 Citations (SciVal)

Abstract

The anticancer active complex cisplatin interacts preferentially with the common, G - C rich, wobble base pair region of both tRNA(Ala) and Mh(Ala) in a reaction that at pH 6.3 is rate limited by the acid hydrolysis of the metal complex.
Original languageEnglish
Pages (from-to)3515-3517
JournalDalton Transactions
Issue number29
DOIs
Publication statusPublished - 2006

Subject classification (UKÄ)

  • Biological Sciences

Fingerprint

Dive into the research topics of 'Kinetic preference for interaction of cisplatin with the G-C-rich wobble basepair region in both tRNA(Ala) and Mh(Ala)'. Together they form a unique fingerprint.

Cite this