Label-free cytometry - Novel sorting parameters and opportunities

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

Abstract

The inherent properties of cells and micro-organisms is an under-explored source of specificity for particle sorting. In contrast to standard immunolabeling it allows us to perform fractionation without any chemical preparation of the sample. This improves the accessibility and affordability of the technology. Our contribution in the field is to extend the scope of deterministic lateral displacement (DLD) from merely a very powerful size-based sorting scheme so that it is used to sort with respect to several other physical parameters. We have explored parameters such as shape, deformability, dielectric properties, secretion and density with potential applications in bacteriology, parasitology and oncology.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages242-245
Number of pages4
ISBN (Electronic)9780979806476
Publication statusPublished - 2014 Jan 1
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: 2014 Oct 262014 Oct 30
Conference number: 18

Conference

Conference18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
Country/TerritoryUnited States
CitySan Antonio
Period2014/10/262014/10/30

Subject classification (UKÄ)

  • Other Physics Topics
  • Analytical Chemistry

Free keywords

  • Biophysics
  • Label free
  • Microfluidics
  • Particle sorting

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