Lean ApoM−/− Mice with Hyperactive Brown Adipose Tissue

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3 Citations (SciVal)


In Cell Reports, Christoffersen et al. [1] demonstrate that sphingosine 1-phosphate (S1P) bound to apolipoprotein M (apoM) regulates the activity and mass of brown adipose tissue (BAT). They found mice lacking apoM to have hyperactive BAT with high triglyceride (TG) utilization, resulting in low white adipose tissue (WAT) mass and low body weight.
Original languageEnglish
Pages (from-to)283-284
JournalTrends in Endocrinology and Metabolism
Issue number5
Early online date2018 Mar 13
Publication statusPublished - 2018 May

Subject classification (UKÄ)

  • Cell and Molecular Biology


  • knockout mice
  • brown adipose tissue


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