LEAP-2, LL-37 and RNase7 in tonsillar tissue: downregulated expression in seasonal allergic rhinitis.

Jesper Bogefors; Anne Månsson; Camilla Rydberg Millrud; Susanna Kumlien Georén; Lars-Olaf Cardell

doi:10.1111/2049-632X.12183

LEAP-2, LL-37 and RNase7 in tonsillar tissue: downregulated expression in seasonal allergic rhinitis.

Jesper Bogefors, Anne Månsson, Camilla Rydberg Millrud, Susanna Kumlien Georén, Lars-Olaf Cardell

Research output: Contribution to journal › Article › peer-review

Abstract

In the upper airway, the production of antimicrobial peptides (AMPs) protects against bacteria, viruses and fungi. Previous investigations have revealed downregulated expression of AMPs in different manifestations of allergic disease. In this study, we examined the expression of LL-37, RNase7 and LEAP-2 in tonsillar tissue and studied a possible relation to seasonal allergic rhinitis (SAR).

Original language	English
Pages (from-to)	55-60
Journal	Pathogens and Disease
Volume	72
Issue number	1
DOIs	https://doi.org/10.1111/2049-632X.12183
Publication status	Published - 2014

Subject classification (UKÄ)

Microbiology in the Medical Area

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10.1111/2049-632X.12183

http://www.ncbi.nlm.nih.gov/pubmed/24821514?dopt=Abstract

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title = "LEAP-2, LL-37 and RNase7 in tonsillar tissue: downregulated expression in seasonal allergic rhinitis.",

abstract = "In the upper airway, the production of antimicrobial peptides (AMPs) protects against bacteria, viruses and fungi. Previous investigations have revealed downregulated expression of AMPs in different manifestations of allergic disease. In this study, we examined the expression of LL-37, RNase7 and LEAP-2 in tonsillar tissue and studied a possible relation to seasonal allergic rhinitis (SAR).",

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AU - Bogefors, Jesper

AU - Månsson, Anne

AU - Millrud, Camilla Rydberg

AU - Georén, Susanna Kumlien

AU - Cardell, Lars-Olaf

PY - 2014

Y1 - 2014

N2 - In the upper airway, the production of antimicrobial peptides (AMPs) protects against bacteria, viruses and fungi. Previous investigations have revealed downregulated expression of AMPs in different manifestations of allergic disease. In this study, we examined the expression of LL-37, RNase7 and LEAP-2 in tonsillar tissue and studied a possible relation to seasonal allergic rhinitis (SAR).

AB - In the upper airway, the production of antimicrobial peptides (AMPs) protects against bacteria, viruses and fungi. Previous investigations have revealed downregulated expression of AMPs in different manifestations of allergic disease. In this study, we examined the expression of LL-37, RNase7 and LEAP-2 in tonsillar tissue and studied a possible relation to seasonal allergic rhinitis (SAR).

U2 - 10.1111/2049-632X.12183

DO - 10.1111/2049-632X.12183

M3 - Article

SN - 2049-632X

VL - 72

SP - 55

EP - 60

JO - Pathogens and Disease

JF - Pathogens and Disease

IS - 1

ER -

LEAP-2, LL-37 and RNase7 in tonsillar tissue: downregulated expression in seasonal allergic rhinitis.

Abstract

Subject classification (UKÄ)

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