LEAP-2, LL-37 and RNase7 in tonsillar tissue: downregulated expression in seasonal allergic rhinitis.

Jesper Bogefors, Anne Månsson, Camilla Rydberg Millrud, Susanna Kumlien Georén, Lars-Olaf Cardell

    Research output: Contribution to journalArticlepeer-review

    8 Citations (SciVal)

    Abstract

    In the upper airway, the production of antimicrobial peptides (AMPs) protects against bacteria, viruses and fungi. Previous investigations have revealed downregulated expression of AMPs in different manifestations of allergic disease. In this study, we examined the expression of LL-37, RNase7 and LEAP-2 in tonsillar tissue and studied a possible relation to seasonal allergic rhinitis (SAR).
    Original languageEnglish
    Pages (from-to)55-60
    JournalPathogens and Disease
    Volume72
    Issue number1
    DOIs
    Publication statusPublished - 2014

    Subject classification (UKÄ)

    • Microbiology in the medical area

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