Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function

Kristian Riesbeck; Arne Forsgren

doi:10.1128/AAC.38.4.879

Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function

Kristian Riesbeck, Arne Forsgren

Clinical Microbiology, Malmö

Skåne University Hospital

Research output: Contribution to journal › Debate/Note/Editorial › peer-review

Abstract

Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.

Original language	English
Pages (from-to)	879-882
Journal	Antimicrobial Agents and Chemotherapy
Volume	38
Issue number	4
DOIs	https://doi.org/10.1128/AAC.38.4.879
Publication status	Published - 1994 Jan 1

Subject classification (UKÄ)

Cancer and Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1128/AAC.38.4.879

Cite this

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title = "Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function",

abstract = "Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.",

author = "Kristian Riesbeck and Arne Forsgren",

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AU - Riesbeck, Kristian

AU - Forsgren, Arne

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N2 - Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.

AB - Temafloxacin increased interleukin-2 production and mRNA levels and enhanced thymidine incorporation in stimulated lymphocyte cultures. Gamma interferon mRNA levels were unaffected. Temafloxacin also stimulated interleukin-2 gene induction, as revealed in a chloramphenicol acetyltransferase reporter gene system. However, temafloxacin exerted significantly weaker effects in these respects than did ciprofloxacin.

U2 - 10.1128/AAC.38.4.879

DO - 10.1128/AAC.38.4.879

M3 - Debate/Note/Editorial

C2 - 8031064

AN - SCOPUS:0028265747

SN - 0066-4804

VL - 38

SP - 879

EP - 882

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 4

ER -

Limited effects of temafloxacin compared with ciprofloxacin on T- lymphocyte function

Abstract

Subject classification (UKÄ)

UN SDGs

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