Looking at hydrogen motions in confinement The uniqueness of Quasi-Elastic Neutron Scattering

J. Fischer, Nikolaos Tsapatsaris, E. de Paula, Heloise Bordallo

    Research output: Contribution to journalReview articlepeer-review

    6 Citations (SciVal)


    Why in a barren and hot desert, clays can contain a significant fraction of water? Why does concrete crack? How can we demonstrate that complexation of a drug does not alter its conformation in a way that affects its functionality? In this paper we present results on various studies using Quasi-Elastic Neutron Scattering aimed at clarifying these questions. To allow for a better understanding of neutron scattering, a brief introduction to the basics of its theory is presented. Following the theoretical part, experimental results dealing with the effects of confinement on the water dynamics caused by the interfaces in clays and the nano- and micro-pores of concrete are reviewed in detail. At the end, recent Quasi-Elastic Neutron Scattering investigations on the complexation of the local anesthetics Bupivacaine (BVC.HCl, C18H28N20.HCl.H2O) and Ropivacaine (RVC.HCl, C17H26N20.HCl.H2O) into the cyclic beta-cyclodextrin oligosaccharide are presented. To conclude, the perspectives that the European Spallation Source brings to this subject are discussed.
    Original languageEnglish
    Pages (from-to)1831-1847
    JournalThe European Physical Journal. Special Topics
    Issue number9
    Publication statusPublished - 2014

    Subject classification (UKÄ)

    • Natural Sciences
    • Physical Sciences


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