Low usefulness of reporting tonsillar PCR Ct-values in pharyngeal infections with Fusobacterium necrophorum

David Nygren; Lisa Wasserstrom; Gustav Torisson; Karin Holm

doi:10.1016/j.anaerobe.2024.102831

Low usefulness of reporting tonsillar PCR Ct-values in pharyngeal infections with Fusobacterium necrophorum

David Nygren, Lisa Wasserstrom, Gustav Torisson, Karin Holm

Skåne University Hospital

Research output: Contribution to journal › Article › peer-review

Abstract

Tonsillar Fusobacterium necrophorum PCR Ct-values were higher in participants with asymptomatic tonsillar carriage than patients with pharyngeal infections. However, Ct-values were not associated with severity of disease or predictive of development of complications and hence lacked clinical usefulness. The reporting of F. necrophorum Ct-values in clinical samples is not recommended.

Original language	English
Article number	102831
Journal	Anaerobe
Volume	86
DOIs	https://doi.org/10.1016/j.anaerobe.2024.102831
Publication status	Published - 2024 Apr

Bibliographical note

Subject classification (UKÄ)

Infectious Medicine

Free keywords

Humans
Fusobacterium necrophorum/genetics
Fusobacterium Infections/microbiology
Male
Polymerase Chain Reaction/methods
Female
Adult
Middle Aged
Palatine Tonsil/microbiology
Young Adult
Adolescent
Aged
Tomography, X-Ray Computed
Carrier State/microbiology

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10.1016/j.anaerobe.2024.102831Licence: CC BY

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title = "Low usefulness of reporting tonsillar PCR Ct-values in pharyngeal infections with Fusobacterium necrophorum",

abstract = "Tonsillar Fusobacterium necrophorum PCR Ct-values were higher in participants with asymptomatic tonsillar carriage than patients with pharyngeal infections. However, Ct-values were not associated with severity of disease or predictive of development of complications and hence lacked clinical usefulness. The reporting of F. necrophorum Ct-values in clinical samples is not recommended.",

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author = "David Nygren and Lisa Wasserstrom and Gustav Torisson and Karin Holm",

year = "2024",

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doi = "10.1016/j.anaerobe.2024.102831",

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AU - Nygren, David

AU - Wasserstrom, Lisa

AU - Torisson, Gustav

AU - Holm, Karin

PY - 2024/4

Y1 - 2024/4

N2 - Tonsillar Fusobacterium necrophorum PCR Ct-values were higher in participants with asymptomatic tonsillar carriage than patients with pharyngeal infections. However, Ct-values were not associated with severity of disease or predictive of development of complications and hence lacked clinical usefulness. The reporting of F. necrophorum Ct-values in clinical samples is not recommended.

AB - Tonsillar Fusobacterium necrophorum PCR Ct-values were higher in participants with asymptomatic tonsillar carriage than patients with pharyngeal infections. However, Ct-values were not associated with severity of disease or predictive of development of complications and hence lacked clinical usefulness. The reporting of F. necrophorum Ct-values in clinical samples is not recommended.

KW - Humans

KW - Fusobacterium necrophorum/genetics

KW - Fusobacterium Infections/microbiology

KW - Male

KW - Polymerase Chain Reaction/methods

KW - Female

KW - Adult

KW - Middle Aged

KW - Palatine Tonsil/microbiology

KW - Young Adult

KW - Adolescent

KW - Aged

KW - Tomography, X-Ray Computed

KW - Carrier State/microbiology

U2 - 10.1016/j.anaerobe.2024.102831

DO - 10.1016/j.anaerobe.2024.102831

M3 - Article

C2 - 38369049

SN - 1095-8274

VL - 86

JO - Anaerobe

JF - Anaerobe

M1 - 102831

ER -

Low usefulness of reporting tonsillar PCR Ct-values in pharyngeal infections with Fusobacterium necrophorum

Abstract

Bibliographical note

Subject classification (UKÄ)

Free keywords

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Cite this