Macroporous gel particles as robust macroporous matrices for cell immobilization

Fatima Plieva, A Oknianska, Eva Degerman, Bo Mattiasson

Research output: Contribution to journalArticlepeer-review

Abstract

A new design of robust matrices for cell immobilization is described. Macroporous gels (MGs) with immobilized microbial cells were prepared at subzero temperatures and were formed inside a plastic core (so-called, protective housing). Due to the protective housing the macroporous gel particles with immobilized cells can be used in well-stirred bioreactors. High retained activity of yeast (77-92%) and Escherichia coli (50-91%) cells immobilized in MGs after drying and storage in the dried state was due to the high structural stability and heterogeneous porous structure of the MGs.
Original languageEnglish
Pages (from-to)410-417
JournalBiotechnology Journal
Volume3
Issue number3
DOIs
Publication statusPublished - 2008

Subject classification (UKÄ)

  • Endocrinology and Diabetes

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