Malignant-tumor and Atherosclerotic Plaque Diagnosis Using Laser-induced Fluorescence

Stefan Andersson-Engels, Jonas Johansson, U Stenram, Katarina Svanberg, Sune Svanberg

Research output: Contribution to journalArticlepeer-review


A review of tissue diagnostics using laser-induced fluorescence is given with illustrations chosen from work performed by the Lund group. Two major topics are considered: the demarcation of malignant tumors from normal surrounding tissue and the identification of atherosclerotic regions in arteries. Specific fluorescence from injected agents as well as tissue natural autofluorescence is discussed. Steady-state, as well as time-resolved fluorescence can be utilized. Furthurmore, original data showing immunity to blood interference in artery monitoring are presented. Finally, imaging techniques for diseased tissue real-time visualization are discussed and illustrated.
Original languageEnglish
Pages (from-to)2207-2217
JournalIEEE Journal of Quantum Electronics
Issue number12
Publication statusPublished - 1990

Subject classification (UKÄ)

  • Atom and Molecular Physics and Optics


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