Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma.

Medya Shikhagaie; Cecilia Andersson; Michiko Mori; I Kortekaas Krohn; Anders Bergqvist; R Dahl; Eva Ekblad; H J Hoffmann; Leif Bjermer; Jonas Erjefält

doi:10.1111/cea.12176

Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma.

Medya Shikhagaie, Cecilia Andersson, Michiko Mori, I Kortekaas Krohn, Anders Bergqvist, R Dahl, Eva Ekblad, H J Hoffmann, Leif Bjermer, Jonas Erjefält

Research output: Contribution to journal › Article › peer-review

Abstract

The toll-like receptors, TLR5 and TLR7, have recently been proposed in asthma immunopathogenesis. While supporting data come from animal or in vitro studies, little is known about TLR5 and TLR7 expression in human asthmatic airways.

Original language	English
Pages (from-to)	184-196
Journal	Clinical and Experimental Allergy
Volume	44
Issue number	2
DOIs	https://doi.org/10.1111/cea.12176
Publication status	Published - 2014

Subject classification (UKÄ)

Immunology in the medical area
Respiratory Medicine and Allergy
Gastroenterology and Hepatology

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10.1111/cea.12176

http://www.ncbi.nlm.nih.gov/pubmed/24447081?dopt=Abstract

Cite this

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title = "Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma.",

abstract = "The toll-like receptors, TLR5 and TLR7, have recently been proposed in asthma immunopathogenesis. While supporting data come from animal or in vitro studies, little is known about TLR5 and TLR7 expression in human asthmatic airways.",

author = "Medya Shikhagaie and Cecilia Andersson and Michiko Mori and {Kortekaas Krohn}, I and Anders Bergqvist and R Dahl and Eva Ekblad and Hoffmann, {H J} and Leif Bjermer and Jonas Erjef{\"a}lt",

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AU - Shikhagaie, Medya

AU - Andersson, Cecilia

AU - Mori, Michiko

AU - Kortekaas Krohn, I

AU - Bergqvist, Anders

AU - Dahl, R

AU - Ekblad, Eva

AU - Hoffmann, H J

AU - Bjermer, Leif

AU - Erjefält, Jonas

PY - 2014

Y1 - 2014

N2 - The toll-like receptors, TLR5 and TLR7, have recently been proposed in asthma immunopathogenesis. While supporting data come from animal or in vitro studies, little is known about TLR5 and TLR7 expression in human asthmatic airways.

AB - The toll-like receptors, TLR5 and TLR7, have recently been proposed in asthma immunopathogenesis. While supporting data come from animal or in vitro studies, little is known about TLR5 and TLR7 expression in human asthmatic airways.

U2 - 10.1111/cea.12176

DO - 10.1111/cea.12176

M3 - Article

C2 - 24447081

SN - 1365-2222

VL - 44

SP - 184

EP - 196

JO - Clinical and Experimental Allergy

JF - Clinical and Experimental Allergy

IS - 2

ER -

Mapping of TLR5 and TLR7 in central and distal human airways and identification of reduced TLR expression in severe asthma.

Abstract

Subject classification (UKÄ)

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Cite this