Mapping the inversion efficiency (finv):
Comparison between adiabatic pulses for use in MP2RAGE-based T1-mapping

Hampus Olsson; Gunther Helms

Mapping the inversion efficiency (f_inv): Comparison between adiabatic pulses for use in MP2RAGE-based T₁-mapping

MR Physics

Research output: Chapter in Book/Report/Conference proceeding › Paper in conference proceeding › peer-review

Abstract

Accuracy in MP2RAGE-based T₁-mapping relies on knowledge of the imperfect inversion efficiency (f_inv) of the inversion pulse. Here we map the inversion efficiency of different adiabatic inversion pulses in human brain at 7T. We identified a mean f_inv=0.86, which is substantially lower than the f_inv=0.96 typically assumed in MP2RAGE. We further observed a lower f_inv in white matter (WM) than in the rest of the cerebrum. Subsequent T₁ estimates differed by approximately 90 ms in WM and 230 ms in GM when assuming either f_inv=0.86 or f_inv=0.96.

Original language	English
Title of host publication	Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition
Place of Publication	Concord, CA
Publisher	International Society for Magnetic Resonance in Medicine
Volume	30
Publication status	Published - 2022 Apr 22
Event	Joint Annual Meeting ISMRM-ESMRMB 2022 - Excel Exhibition Centre, London, United Kingdom Duration: 2022 May 7 → 2022 May 12 https://www.ismrm.org/22m/

Publication series

Name	Proc Intl Soc Magn Reson Med
Publisher	Intl. Society for Magnetic Resonance in Medicine (ISMRM)
Volume	30
ISSN (Electronic)	1545-4428

Conference

Conference	Joint Annual Meeting ISMRM-ESMRMB 2022
Country/Territory	United Kingdom
City	London
Period	2022/05/07 → 2022/05/12
Internet address	https://www.ismrm.org/22m/

Subject classification (UKÄ)

Radiology and Medical Imaging
Other Physics Topics

Access to Document

https://index.mirasmart.com/ISMRM2022/PDFfiles/0372.htmlLicence: Unspecified

Cite this

Olsson, H., & Helms, G. (2022). Mapping the inversion efficiency (f_inv): Comparison between adiabatic pulses for use in MP2RAGE-based T₁-mapping. In Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition (Vol. 30). Article 372 (Proc Intl Soc Magn Reson Med; Vol. 30). International Society for Magnetic Resonance in Medicine. https://index.mirasmart.com/ISMRM2022/PDFfiles/0372.html

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title = "Mapping the inversion efficiency (finv): Comparison between adiabatic pulses for use in MP2RAGE-based T1-mapping",

abstract = "Accuracy in MP2RAGE-based T1-mapping relies on knowledge of the imperfect inversion efficiency (finv) of the inversion pulse. Here we map the inversion efficiency of different adiabatic inversion pulses in human brain at 7T. We identified a mean finv=0.86, which is substantially lower than the finv=0.96 typically assumed in MP2RAGE. We further observed a lower finv in white matter (WM) than in the rest of the cerebrum. Subsequent T1 estimates differed by approximately 90 ms in WM and 230 ms in GM when assuming either finv=0.86 or finv=0.96. ",

author = "Hampus Olsson and Gunther Helms",

year = "2022",

month = apr,

day = "22",

language = "English",

volume = "30",

series = "Proc Intl Soc Magn Reson Med",

publisher = "International Society for Magnetic Resonance in Medicine",

booktitle = "Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition",

note = "Joint Annual Meeting ISMRM-ESMRMB 2022 ; Conference date: 07-05-2022 Through 12-05-2022",

url = "https://www.ismrm.org/22m/",

}

Olsson, H & Helms, G 2022, Mapping the inversion efficiency (f_inv): Comparison between adiabatic pulses for use in MP2RAGE-based T₁-mapping. in Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition. vol. 30, 372, Proc Intl Soc Magn Reson Med, vol. 30, International Society for Magnetic Resonance in Medicine, Concord, CA, Joint Annual Meeting ISMRM-ESMRMB 2022, London, United Kingdom, 2022/05/07. <https://index.mirasmart.com/ISMRM2022/PDFfiles/0372.html>

Mapping the inversion efficiency (f_inv): Comparison between adiabatic pulses for use in MP2RAGE-based T₁-mapping. / Olsson, Hampus; Helms, Gunther.
Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition. Vol. 30 Concord, CA: International Society for Magnetic Resonance in Medicine, 2022. 372 (Proc Intl Soc Magn Reson Med; Vol. 30).

Research output: Chapter in Book/Report/Conference proceeding › Paper in conference proceeding › peer-review

TY - GEN

T1 - Mapping the inversion efficiency (finv): Comparison between adiabatic pulses for use in MP2RAGE-based T1-mapping

AU - Olsson, Hampus

AU - Helms, Gunther

PY - 2022/4/22

Y1 - 2022/4/22

N2 - Accuracy in MP2RAGE-based T1-mapping relies on knowledge of the imperfect inversion efficiency (finv) of the inversion pulse. Here we map the inversion efficiency of different adiabatic inversion pulses in human brain at 7T. We identified a mean finv=0.86, which is substantially lower than the finv=0.96 typically assumed in MP2RAGE. We further observed a lower finv in white matter (WM) than in the rest of the cerebrum. Subsequent T1 estimates differed by approximately 90 ms in WM and 230 ms in GM when assuming either finv=0.86 or finv=0.96.

AB - Accuracy in MP2RAGE-based T1-mapping relies on knowledge of the imperfect inversion efficiency (finv) of the inversion pulse. Here we map the inversion efficiency of different adiabatic inversion pulses in human brain at 7T. We identified a mean finv=0.86, which is substantially lower than the finv=0.96 typically assumed in MP2RAGE. We further observed a lower finv in white matter (WM) than in the rest of the cerebrum. Subsequent T1 estimates differed by approximately 90 ms in WM and 230 ms in GM when assuming either finv=0.86 or finv=0.96.

M3 - Paper in conference proceeding

VL - 30

T3 - Proc Intl Soc Magn Reson Med

BT - Proceedings of the 2022 ISMRM & ISMRT Annual Meeting and Exhibition

PB - International Society for Magnetic Resonance in Medicine

CY - Concord, CA

T2 - Joint Annual Meeting ISMRM-ESMRMB 2022

Y2 - 7 May 2022 through 12 May 2022

ER -

Mapping the inversion efficiency (f_inv): Comparison between adiabatic pulses for use in MP2RAGE-based T₁-mapping

Abstract

Publication series

Conference

Subject classification (UKÄ)

Access to Document

Other files and links

Fingerprint

Gradient echo-based quantitative MRI of human brain at 7T: Mapping of T1, MT saturation and local flip angle

Gradient echo-based quantitative MRI of human brain at 7T

Multiparametric mapping of the brain at 7T using gradient echoes

Lund University Bioimaging Center

Cite this

Mapping the inversion efficiency (finv): Comparison between adiabatic pulses for use in MP2RAGE-based T1-mapping

Abstract

Publication series

Conference

Subject classification (UKÄ)

Access to Document

Other files and links

Fingerprint

Research output

Gradient echo-based quantitative MRI of human brain at 7T: Mapping of T1, MT saturation and local flip angle

Projects

Gradient echo-based quantitative MRI of human brain at 7T

Multiparametric mapping of the brain at 7T using gradient echoes

Equipment

Lund University Bioimaging Center

Cite this

Mapping the inversion efficiency (f_inv): Comparison between adiabatic pulses for use in MP2RAGE-based T₁-mapping