Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly

Björn Hultberg; Anders Isaksson; Karin Nilsson; Lars Gustafson

doi:10.1002/gps.439

Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly

Björn Hultberg, Anders Isaksson, Karin Nilsson, Lars Gustafson

Research output: Contribution to journal › Article › peer-review

Abstract

Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non-organic mental diseases. This paper reviews the literature relevant for markers of cobalamin/folate status and their relation to neuropsychiatric symptoms in the elderly. Plasma homocysteine, a marker of cobalamin/folate status, is frequently increased in psychogeriatric patients. Among markers of cobalamin/folate status, plasma homocysteine shows the best association with neuropsychiatric dysfunction.

Original language	English
Pages (from-to)	873-878
Journal	International Journal of Geriatric Psychiatry
Volume	16
Issue number	9
DOIs	https://doi.org/10.1002/gps.439
Publication status	Published - 2001

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Department of Psychogeriatrics (013304000)

Subject classification (UKÄ)

Geriatrics
Psychiatry

Free keywords

blood
cobalamin
folate
homocysteine
methylmalonic acid
plasma
psychogeriatric patients

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10.1002/gps.439

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abstract = "Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non-organic mental diseases. This paper reviews the literature relevant for markers of cobalamin/folate status and their relation to neuropsychiatric symptoms in the elderly. Plasma homocysteine, a marker of cobalamin/folate status, is frequently increased in psychogeriatric patients. Among markers of cobalamin/folate status, plasma homocysteine shows the best association with neuropsychiatric dysfunction.",

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author = "Bj{\"o}rn Hultberg and Anders Isaksson and Karin Nilsson and Lars Gustafson",

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doi = "10.1002/gps.439",

language = "English",

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journal = "International Journal of Geriatric Psychiatry",

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T1 - Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly

AU - Hultberg, Björn

AU - Isaksson, Anders

AU - Nilsson, Karin

AU - Gustafson, Lars

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Department of Psychogeriatrics (013304000)

PY - 2001

Y1 - 2001

N2 - Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non-organic mental diseases. This paper reviews the literature relevant for markers of cobalamin/folate status and their relation to neuropsychiatric symptoms in the elderly. Plasma homocysteine, a marker of cobalamin/folate status, is frequently increased in psychogeriatric patients. Among markers of cobalamin/folate status, plasma homocysteine shows the best association with neuropsychiatric dysfunction.

AB - Cobalamin/folate deficiency is common in elderly subjects and may lead to psychiatric symptoms, but even more often it increases the severity of other organic and non-organic mental diseases. This paper reviews the literature relevant for markers of cobalamin/folate status and their relation to neuropsychiatric symptoms in the elderly. Plasma homocysteine, a marker of cobalamin/folate status, is frequently increased in psychogeriatric patients. Among markers of cobalamin/folate status, plasma homocysteine shows the best association with neuropsychiatric dysfunction.

KW - blood

KW - cobalamin

KW - folate

KW - homocysteine

KW - methylmalonic acid

KW - plasma

KW - psychogeriatric patients

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DO - 10.1002/gps.439

M3 - Article

SN - 1099-1166

VL - 16

SP - 873

EP - 878

JO - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

IS - 9

ER -

Markers for the functional availability of cobalamin/folate and their association with neuropsychiatric symptoms in the elderly

Abstract

Bibliographical note

Subject classification (UKÄ)

Free keywords

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