Melting mapping in nanochannels

Walter W. Reisner; Henrik Flyvbjerg; Jonas O. Tegenfeldt

Melting mapping in nanochannels

Walter W. Reisner, Henrik Flyvbjerg, Jonas O. Tegenfeldt

Solid State Physics

Research output: Contribution to conference › Paper, not in proceeding › peer-review

Abstract

We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.

Original language	English
Pages	1516-1518
Number of pages	3
Publication status	Published - 2008 Jan 1
Event	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16

Conference

Conference	12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008
Country/Territory	United States
City	San Diego, CA
Period	2008/10/12 → 2008/10/16

Free keywords

DNA
Genomics
Melting
Nanofluidics

Cite this

@conference{6b02dea2ceab47e38ed0ebc37b5106aa,

title = "Melting mapping in nanochannels",

abstract = "We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.",

keywords = "DNA, Genomics, Melting, Nanofluidics",

author = "Reisner, {Walter W.} and Henrik Flyvbjerg and Tegenfeldt, {Jonas O.}",

year = "2008",

month = jan,

day = "1",

language = "English",

pages = "1516--1518",

note = "12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 ; Conference date: 12-10-2008 Through 16-10-2008",

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TY - CONF

T1 - Melting mapping in nanochannels

AU - Reisner, Walter W.

AU - Flyvbjerg, Henrik

AU - Tegenfeldt, Jonas O.

PY - 2008/1/1

Y1 - 2008/1/1

N2 - We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.

AB - We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.

KW - DNA

KW - Genomics

KW - Melting

KW - Nanofluidics

UR - http://www.scopus.com/inward/record.url?scp=84902504260&partnerID=8YFLogxK

M3 - Paper, not in proceeding

AN - SCOPUS:84902504260

SP - 1516

EP - 1518

T2 - 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008

Y2 - 12 October 2008 through 16 October 2008

ER -

Melting mapping in nanochannels

Abstract

Conference

Free keywords

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Cite this