Abstract
We demonstrate direct visualization of melting mapping of DNA stretched in nanoscale channels[1] using standard staining methods and epifluorescence microscopy to gain information on the local AT/GC ratio along large DNA molecules. Our development opens up a novel route to mapping of large-scale genomic variations.
Original language | English |
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Pages | 1516-1518 |
Number of pages | 3 |
Publication status | Published - 2008 Jan 1 |
Event | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA, United States Duration: 2008 Oct 12 → 2008 Oct 16 |
Conference
Conference | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
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Country/Territory | United States |
City | San Diego, CA |
Period | 2008/10/12 → 2008/10/16 |
Free keywords
- DNA
- Genomics
- Melting
- Nanofluidics