Method for Programming Differentiated Cells into Hematopoietic Stem Cells

Ihor R. Lemischka (Inventor), Kateri Moore (Inventor), Filipe Pereira (Inventor)

Research output: Patent

Abstract

The disclosure relates to the development of methods for making hematopoietic stem cells from differentiated cells by introducing and expressing transcription factors. More particularly, the disclosure provides methods for redirecting differentiated cells to a hematopoietic stem cell state or to a hemogenic endothelial cell state by direct programming with specific combinations of transcription factors.
Original languageEnglish
Patent numberWO2013116307A1
Filing date2013/01/30
Publication statusPublished - 2017
Externally publishedYes

Subject classification (UKÄ)

  • Cell and Molecular Biology

Fingerprint

Dive into the research topics of 'Method for Programming Differentiated Cells into Hematopoietic Stem Cells'. Together they form a unique fingerprint.

Cite this