Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results

C-E Lindholm; Elisabeth Kjellén; Torsten Landberg; Per Nilsson; B Persson

doi:10.3109/02841868209134013

Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results

C-E Lindholm, Elisabeth Kjellén, Torsten Landberg, Per Nilsson, B Persson

Research output: Contribution to journal › Article › peer-review

Abstract

The combination of microwave-induced (2450 MHz) hyperthermia and ionizing radiation was used in 7 patients with superficial malignant tumours, which were considered refractory to other therapy. A newly developed heating system was used, allowing for a maintained temperature at the master probe of 42.5 degrees C +/- 0.5 degrees C during 45 min, but temperature measurements at multiple sites showed a marked variation. This preliminary series indicates that the combination of hyperthermia and ionizing radiation may be useful, the response rate (complete or partial) being 8 of 8 evaluable lesions. Even previously heavily irradiated sites responded. Technical improvements are highly needed to allow for controlled heating of any tissue volume.

Original language	English
Pages (from-to)	241-254
Journal	Acta Radiologica: Oncology
Volume	21
Issue number	4
DOIs	https://doi.org/10.3109/02841868209134013
Publication status	Published - 1982

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Oncology, MV (013035000), Emergency medicine/Medicine/Surgery (013240200), Radiation Physics, Lund (013034000)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Subject classification (UKÄ)

Cancer and Oncology
Clinical Medicine
Radiology and Medical Imaging

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10.3109/02841868209134013

Cite this

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title = "Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results",

abstract = "The combination of microwave-induced (2450 MHz) hyperthermia and ionizing radiation was used in 7 patients with superficial malignant tumours, which were considered refractory to other therapy. A newly developed heating system was used, allowing for a maintained temperature at the master probe of 42.5 degrees C +/- 0.5 degrees C during 45 min, but temperature measurements at multiple sites showed a marked variation. This preliminary series indicates that the combination of hyperthermia and ionizing radiation may be useful, the response rate (complete or partial) being 8 of 8 evaluable lesions. Even previously heavily irradiated sites responded. Technical improvements are highly needed to allow for controlled heating of any tissue volume.",

author = "C-E Lindholm and Elisabeth Kjell{\'e}n and Torsten Landberg and Per Nilsson and B Persson",

note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Oncology, MV (013035000), Emergency medicine/Medicine/Surgery (013240200), Radiation Physics, Lund (013034000)",

year = "1982",

doi = "10.3109/02841868209134013",

language = "English",

volume = "21",

pages = "241--254",

journal = "Acta Radiologica: Oncology",

issn = "0349-652X",

publisher = "Taylor \& Francis",

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T1 - Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results

AU - Lindholm, C-E

AU - Kjellén, Elisabeth

AU - Landberg, Torsten

AU - Nilsson, Per

AU - Persson, B

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Oncology, MV (013035000), Emergency medicine/Medicine/Surgery (013240200), Radiation Physics, Lund (013034000)

PY - 1982

Y1 - 1982

N2 - The combination of microwave-induced (2450 MHz) hyperthermia and ionizing radiation was used in 7 patients with superficial malignant tumours, which were considered refractory to other therapy. A newly developed heating system was used, allowing for a maintained temperature at the master probe of 42.5 degrees C +/- 0.5 degrees C during 45 min, but temperature measurements at multiple sites showed a marked variation. This preliminary series indicates that the combination of hyperthermia and ionizing radiation may be useful, the response rate (complete or partial) being 8 of 8 evaluable lesions. Even previously heavily irradiated sites responded. Technical improvements are highly needed to allow for controlled heating of any tissue volume.

AB - The combination of microwave-induced (2450 MHz) hyperthermia and ionizing radiation was used in 7 patients with superficial malignant tumours, which were considered refractory to other therapy. A newly developed heating system was used, allowing for a maintained temperature at the master probe of 42.5 degrees C +/- 0.5 degrees C during 45 min, but temperature measurements at multiple sites showed a marked variation. This preliminary series indicates that the combination of hyperthermia and ionizing radiation may be useful, the response rate (complete or partial) being 8 of 8 evaluable lesions. Even previously heavily irradiated sites responded. Technical improvements are highly needed to allow for controlled heating of any tissue volume.

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DO - 10.3109/02841868209134013

M3 - Article

SN - 0349-652X

VL - 21

SP - 241

EP - 254

JO - Acta Radiologica: Oncology

JF - Acta Radiologica: Oncology

IS - 4

ER -

Microwave-induced hyperthermia and ionizing radiation. Preliminary clinical results

Abstract

Bibliographical note

UN SDGs

Subject classification (UKÄ)

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