Molecular docking analysis of ahl molecule on plant protein arr10

Anamika Basu, Anasua Sarkar

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

Abstract

In rhizosphere Plant Growth Promoting Rhizobacteria (PGPR) produce N-acyl-l-homoserine lactones (AHL) as the quorum-sensing (QS) signals. AHLs can act as trans-kingdom signalling molecules between plants and rhizobacteria and that can regulate plant growth and development. The plant-beneficial PGPR Burkholderia phytofirmans PsJN promotes growth in Arabidopsis thaliana by producing 3-oxo-dodecanoyl homoserine lactone (oxo-C14-HSL) from their quorum-sensing (QS) system. In bacteria, QS system functions by binding AHL to the LuxR-family of sensor/regulator proteins through their response regulator receiver domain. It has been hypothesized that by using similar response domain, Arabidopsis response regulator 10 (ARR10) proteins may act as binding site for 3-oxo-dodecanoyl homoserine lactone. ARRs are involved in cytokinin signalling pathways and thus these types of lactones can regulate growth in Arabidopsis. We prove the binding of oxo-C14-HSL with ARR10 by using molecular docking technique and analysing the docking result.

Original languageEnglish
Title of host publicationInformation Systems Design and Intelligent Applications - Proceedings of 2nd International Conference, INDIA 2015
EditorsJ.K. Mandal, Suresh Chandra Satapathy, Manas Kumar Sanyal, Partha Pratim Sarkar, Anirban Mukhopadhyay
PublisherSpringer
Pages187-193
ISBN (Electronic)9788132222460
DOIs
Publication statusPublished - 2015 Jan 1
Externally publishedYes
Event2nd International Conference on Information Systems Design and Intelligent Applications, INDIA 2015 - Kalyani, India
Duration: 2015 Jan 82015 Jan 9

Publication series

NameAdvances in Intelligent Systems and Computing
Volume340
ISSN (Print)2194-5357

Conference

Conference2nd International Conference on Information Systems Design and Intelligent Applications, INDIA 2015
Country/TerritoryIndia
CityKalyani
Period2015/01/082015/01/09

Free keywords

  • 3-oxo-C14-Homo serine lactones
  • Arabidopsis response regulator 10 (ARR10) proteins
  • Burkholderia phytofirmans PsJN
  • Molecular docking
  • N-acyl-l-homoserine lactones
  • Plant growth promoting rhizobacteria
  • Response regulator receiver domain

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