Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.

Marianna Yanez; Debora Berti; Costanza Montis; Richard A Campbell; Luke A Clifton; Maximilian W A Skoda; Olaf Soltwedel; Piero Baglioni; Tommy Nylander

doi:10.1039/c4sm01733a

Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.

Marianna Yanez, Debora Berti, Costanza Montis, Richard A Campbell, Luke A Clifton, Maximilian W A Skoda, Olaf Soltwedel, Piero Baglioni, Tommy Nylander

Physical Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.

Original language	English
Pages (from-to)	8401-8405
Journal	Soft Matter
Volume	10
Issue number	42
DOIs	https://doi.org/10.1039/c4sm01733a
Publication status	Published - 2014

Subject classification (UKÄ)

Physical Chemistry (including Surface- and Colloid Chemistry)

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10.1039/c4sm01733a

Cite this

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title = "Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.",

abstract = "We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.",

author = "Marianna Yanez and Debora Berti and Costanza Montis and Campbell, \{Richard A\} and Clifton, \{Luke A\} and Skoda, \{Maximilian W A\} and Olaf Soltwedel and Piero Baglioni and Tommy Nylander",

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T1 - Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.

AU - Yanez, Marianna

AU - Berti, Debora

AU - Montis, Costanza

AU - Campbell, Richard A

AU - Clifton, Luke A

AU - Skoda, Maximilian W A

AU - Soltwedel, Olaf

AU - Baglioni, Piero

AU - Nylander, Tommy

PY - 2014

Y1 - 2014

N2 - We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.

AB - We show for the first time that 1,2-dilauroyl-sn-glycero-3-phosphatidyladenosine nucleolipid surface complexes with cationic poly(amidoamine) dendrimers can be used to selectively bind DNA including oligonucleotides. This molecular recognition has high potential for applications involving biomedical and bioanalytic devices as well as drug delivery systems based on nucleic acids.

UR - https://www.scopus.com/pages/publications/84924043635

U2 - 10.1039/c4sm01733a

DO - 10.1039/c4sm01733a

M3 - Article

C2 - 25246334

SN - 1744-6848

VL - 10

SP - 8401

EP - 8405

JO - Soft Matter

JF - Soft Matter

IS - 42

ER -

Molecular recognition of nucleic acids by nucleolipid/dendrimer surface complexes.

Abstract

Subject classification (UKÄ)

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