Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes.

Jenny-Maria Jönsson; Ida Johansson; Mev Dominguez; Siker Kimbung; Mats Jönsson; Jesper Hansen Bonde; Päivi Kannisto; Anna Måsbäck; Susanne Malander; Mef Nilbert; Ingrid Hedenfalk

doi:10.1371/journal.pone.0107643

Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes.

Jenny-Maria Jönsson, Ida Johansson, Mev Dominguez, Siker Kimbung, Mats Jönsson, Jesper Hansen Bonde, Päivi Kannisto, Anna Måsbäck, Susanne Malander, Mef Nilbert, Ingrid Hedenfalk

Research output: Contribution to journal › Article › peer-review

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Abstract

Transcriptional profiling of epithelial ovarian cancer has revealed molecular subtypes correlating to biological and clinical features. We aimed to determine gene expression differences between malignant, benign and borderline serous ovarian tumors, and investigate similarities with the well-established intrinsic molecular subtypes of breast cancer.

Original language	English
Article number	e107643
Journal	PLoS ONE
Volume	9
Issue number	9
DOIs	https://doi.org/10.1371/journal.pone.0107643
Publication status	Published - 2014

Subject classification (UKÄ)

Cancer and Oncology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1371/journal.pone.0107643

PLoS__Jonsson_et_al

http://www.ncbi.nlm.nih.gov/pubmed/25226589?dopt=Abstract

1 Doctoral Thesis (compilation)

Intrinsic subtypes and prognostic implications in epithelial ovarian cancer
Jönsson, J.-M., 2015, Division of Oncology and Pathology, Lund University. 111 p.
Research output: Thesis › Doctoral Thesis (compilation)

File

Precision Medicine in Hereditary Cancer and Sarcoma; targeted surveillance, immunotherapy and individualized follow-up
Nilbert, M. (PI), Rambech, E. (Researcher), Jönsson, M. (Researcher), Styring, E. (Assistant supervisor), Nyström, H. (Research student) & Rosell, L. (Research student)
Project: Research

Cite this

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title = "Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes.",

abstract = "Transcriptional profiling of epithelial ovarian cancer has revealed molecular subtypes correlating to biological and clinical features. We aimed to determine gene expression differences between malignant, benign and borderline serous ovarian tumors, and investigate similarities with the well-established intrinsic molecular subtypes of breast cancer.",

author = "Jenny-Maria J{\"o}nsson and Ida Johansson and Mev Dominguez and Siker Kimbung and Mats J{\"o}nsson and Bonde, {Jesper Hansen} and P{\"a}ivi Kannisto and Anna M{\aa}sb{\"a}ck and Susanne Malander and Mef Nilbert and Ingrid Hedenfalk",

year = "2014",

doi = "10.1371/journal.pone.0107643",

language = "English",

volume = "9",

journal = "PLoS ONE",

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T1 - Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes.

AU - Jönsson, Jenny-Maria

AU - Johansson, Ida

AU - Dominguez, Mev

AU - Kimbung, Siker

AU - Jönsson, Mats

AU - Bonde, Jesper Hansen

AU - Kannisto, Päivi

AU - Måsbäck, Anna

AU - Malander, Susanne

AU - Nilbert, Mef

AU - Hedenfalk, Ingrid

PY - 2014

Y1 - 2014

N2 - Transcriptional profiling of epithelial ovarian cancer has revealed molecular subtypes correlating to biological and clinical features. We aimed to determine gene expression differences between malignant, benign and borderline serous ovarian tumors, and investigate similarities with the well-established intrinsic molecular subtypes of breast cancer.

AB - Transcriptional profiling of epithelial ovarian cancer has revealed molecular subtypes correlating to biological and clinical features. We aimed to determine gene expression differences between malignant, benign and borderline serous ovarian tumors, and investigate similarities with the well-established intrinsic molecular subtypes of breast cancer.

U2 - 10.1371/journal.pone.0107643

DO - 10.1371/journal.pone.0107643

M3 - Article

C2 - 25226589

SN - 1932-6203

VL - 9

JO - PLoS ONE

JF - PLoS ONE

IS - 9

M1 - e107643

ER -

Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes.

Abstract

Subject classification (UKÄ)

UN SDGs

Access to Document

Fingerprint

Research output

Intrinsic subtypes and prognostic implications in epithelial ovarian cancer

Projects

Precision Medicine in Hereditary Cancer and Sarcoma; targeted surveillance, immunotherapy and individualized follow-up

Cite this