Molecular subtyping of serous ovarian tumors reveals multiple connections to intrinsic breast cancer subtypes.

Jenny-Maria Jönsson, Ida Johansson, Mev Dominguez, Siker Kimbung, Mats Jönsson, Jesper Hansen Bonde, Päivi Kannisto, Anna Måsbäck, Susanne Malander, Mef Nilbert, Ingrid Hedenfalk

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Abstract

Transcriptional profiling of epithelial ovarian cancer has revealed molecular subtypes correlating to biological and clinical features. We aimed to determine gene expression differences between malignant, benign and borderline serous ovarian tumors, and investigate similarities with the well-established intrinsic molecular subtypes of breast cancer.
Original languageEnglish
Article numbere107643
JournalPLoS ONE
Volume9
Issue number9
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Cancer and Oncology

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