Molekylär medicin: Molekylärgenetisk metodik avslöjar mekanismerna bakom tumörutveckling

Translated title of the contribution: Molecular genetics methods discovering the mechanisms of neoplasm etiology

Thoas Fioretos, Pierre Åman

Research output: Contribution to journalArticlepeer-review

Abstract

The rapid advance in our understanding of cancer biology during the past decade, as exemplified by the discovery of oncogenes and tumour suppressor genes and their interactions in tumourigenesis, has revolutionized cancer research. This rapid progress has largely been due to the use of molecular genetics techniques. However, despite the wealth of available information as to the genetic basis of carcinogenesis, its clinical applicability remains limited. The review is a summary of the general principles and methods currently used to detect genetic alterations in neoplastic cells, with special emphasis on clinical applications.
Translated title of the contributionMolecular genetics methods discovering the mechanisms of neoplasm etiology
Original languageSwedish
Pages (from-to)2597-2602
JournalLäkartidningen
Volume88
Issue number32-33
Publication statusPublished - 1991

Subject classification (UKÄ)

  • Medical Genetics

Free keywords

  • Molekylärbiologi
  • Biokemisk genetik
  • Neoplastisk celltransformation
  • Genetiska tekniker

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