MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle

Olof Asplund; Johan Rung; Leif Groop; Rashmi Prasad B; Ola Hansson

doi:10.1093/database/baaa111

MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle

Olof Asplund, Johan Rung, Leif Groop, Rashmi Prasad B, Ola Hansson

Research output: Contribution to journal › Article › peer-review

Abstract

MuscleAtlasExplorer is a freely available web application that allows for the exploration of gene expression data from human skeletal muscle. It draws from an extensive publicly available dataset of 1654 skeletal muscle expression microarray samples. Detailed, manually curated, patient phenotype data, with information such as age, sex, BMI and disease status, are combined with skeletal muscle gene expression to provide insights into gene function in skeletal muscle. It aims to facilitate easy exploration of the data using powerful data visualization functions, while allowing for sample selection, in-depth inspection and further analysis using external tools. Availability: MuscleAtlasExplorer is available at https://mae.crc.med.lu.se/mae2 (username 'muscle' and password 'explorer' pre-publication).

Original language	English
Article number	baaa111
Journal	Database: the journal of biological databases and curation
Volume	2020
DOIs	https://doi.org/10.1093/database/baaa111
Publication status	Published - 2020 Dec 18

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Subject classification (UKÄ)

Bioinformatics and Computational Biology
Medical Genetics and Genomics (including Gene Therapy)

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database tool

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10.1093/database/baaa111Licence: CC BY

Cite this

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title = "MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle",

abstract = "MuscleAtlasExplorer is a freely available web application that allows for the exploration of gene expression data from human skeletal muscle. It draws from an extensive publicly available dataset of 1654 skeletal muscle expression microarray samples. Detailed, manually curated, patient phenotype data, with information such as age, sex, BMI and disease status, are combined with skeletal muscle gene expression to provide insights into gene function in skeletal muscle. It aims to facilitate easy exploration of the data using powerful data visualization functions, while allowing for sample selection, in-depth inspection and further analysis using external tools. Availability: MuscleAtlasExplorer is available at https://mae.crc.med.lu.se/mae2 (username 'muscle' and password 'explorer' pre-publication).",

keywords = "database tool",

author = "Olof Asplund and Johan Rung and Leif Groop and \{Prasad B\}, Rashmi and Ola Hansson",

note = "{\textcopyright} The Author(s) 2020. Published by Oxford University Press.",

year = "2020",

month = dec,

day = "18",

doi = "10.1093/database/baaa111",

language = "English",

volume = "2020",

journal = "Database: the journal of biological databases and curation",

issn = "1758-0463",

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}

TY - JOUR

T1 - MuscleAtlasExplorer

T2 - a web service for studying gene expression in human skeletal muscle

AU - Asplund, Olof

AU - Rung, Johan

AU - Groop, Leif

AU - Prasad B, Rashmi

AU - Hansson, Ola

PY - 2020/12/18

Y1 - 2020/12/18

N2 - MuscleAtlasExplorer is a freely available web application that allows for the exploration of gene expression data from human skeletal muscle. It draws from an extensive publicly available dataset of 1654 skeletal muscle expression microarray samples. Detailed, manually curated, patient phenotype data, with information such as age, sex, BMI and disease status, are combined with skeletal muscle gene expression to provide insights into gene function in skeletal muscle. It aims to facilitate easy exploration of the data using powerful data visualization functions, while allowing for sample selection, in-depth inspection and further analysis using external tools. Availability: MuscleAtlasExplorer is available at https://mae.crc.med.lu.se/mae2 (username 'muscle' and password 'explorer' pre-publication).

AB - MuscleAtlasExplorer is a freely available web application that allows for the exploration of gene expression data from human skeletal muscle. It draws from an extensive publicly available dataset of 1654 skeletal muscle expression microarray samples. Detailed, manually curated, patient phenotype data, with information such as age, sex, BMI and disease status, are combined with skeletal muscle gene expression to provide insights into gene function in skeletal muscle. It aims to facilitate easy exploration of the data using powerful data visualization functions, while allowing for sample selection, in-depth inspection and further analysis using external tools. Availability: MuscleAtlasExplorer is available at https://mae.crc.med.lu.se/mae2 (username 'muscle' and password 'explorer' pre-publication).

KW - database tool

UR - https://www.scopus.com/pages/publications/85098743695

U2 - 10.1093/database/baaa111

DO - 10.1093/database/baaa111

M3 - Article

C2 - 33338203

SN - 1758-0463

VL - 2020

JO - Database: the journal of biological databases and curation

JF - Database: the journal of biological databases and curation

M1 - baaa111

ER -

MuscleAtlasExplorer: a web service for studying gene expression in human skeletal muscle

Abstract

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