New chromosomal rearrangement, t(12;22)(p13;q12), in acute nonlymphocytic leukemia

David F Callen, Yvonne J Hull, Ian R Toogood, Thoas Fioretos, Sverre Heim, Nils Mandahl, Felix Mitelman

Research output: Contribution to journalArticlepeer-review

Abstract

The karyotype 47,XX, + 8,t(12;22)(p13;q12) was found at diagnosis in two patients with acute nonlymphocytic leukemia (ANLL). The bone marrow morphology of both patients corresponded to the M4 subtype of the French-American-British (FAB) classification. The translocation t(12;22) has not previously been reported as the sole structural aberration in ANLL.
Original languageEnglish
Pages (from-to)255-258
JournalCancer Genetics and Cytogenetics
Volume51
Issue number2
DOIs
Publication statusPublished - 1991

Subject classification (UKÄ)

  • Medical Genetics and Genomics (including Gene Therapy)

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