No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

M. D. Kaspersen; Mona Bungum; J. Fedder; J. Bonde; P. B. Larsen; H. J. Ingerslev; P. Hollsberg

doi:10.1111/j.2047-2927.2013.00067.x

No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

M. D. Kaspersen, Mona Bungum, J. Fedder, J. Bonde, P. B. Larsen, H. J. Ingerslev, P. Hollsberg

Reproductive medicine, Malmö

Research output: Contribution to journal › Article › peer-review

Abstract

It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.

Original language	English
Pages (from-to)	361-364
Journal	Andrology
Volume	1
Issue number	3
DOIs	https://doi.org/10.1111/j.2047-2927.2013.00067.x
Publication status	Published - 2013

Subject classification (UKÄ)

Gynaecology, Obstetrics and Reproductive Medicine

Free keywords

human herpesvirus
human papillomavirus
Sperm Chromatin Structure
Assay
sperm DNA fragmentation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.2047-2927.2013.00067.x

Cite this

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title = "No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus",

abstract = "It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.",

keywords = "human herpesvirus, human papillomavirus, Sperm Chromatin Structure, Assay, sperm DNA fragmentation",

author = "Kaspersen, {M. D.} and Mona Bungum and J. Fedder and J. Bonde and Larsen, {P. B.} and Ingerslev, {H. J.} and P. Hollsberg",

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T1 - No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

AU - Kaspersen, M. D.

AU - Bungum, Mona

AU - Fedder, J.

AU - Bonde, J.

AU - Larsen, P. B.

AU - Ingerslev, H. J.

AU - Hollsberg, P.

PY - 2013

Y1 - 2013

N2 - It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.

AB - It remains unknown whether human papillomaviruses (HPVs) or human herpesviruses (HHVs) in semen affect sperm DNA integrity. We investigated whether the presence of these viruses in semen was associated with an elevated sperm DNA fragmentation index. Semen from 76 sperm donors was examined by a PCR-based hybridization array that identifies all HHVs and 35 of the most common HPVs. Sperm DNA integrity was determined by the sperm chromatin structure assay. HPVs or HHVs, or both, were found in 57% of semen samples; however, sperm DNA fragmentation index was not increased in semen containing these viruses.

KW - human herpesvirus

KW - human papillomavirus

KW - Sperm Chromatin Structure

KW - Assay

KW - sperm DNA fragmentation

U2 - 10.1111/j.2047-2927.2013.00067.x

DO - 10.1111/j.2047-2927.2013.00067.x

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SN - 2047-2927

VL - 1

SP - 361

EP - 364

JO - Andrology

JF - Andrology

IS - 3

ER -

No increased sperm DNA fragmentation index in semen containing human papillomavirus or herpesvirus

Abstract

Subject classification (UKÄ)

Free keywords

UN SDGs

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Cite this