On hydrophobicity correlations in protein chains

A Irbäck, E Sandelin

Research output: Contribution to journalArticlepeer-review

49 Citations (SciVal)

Abstract

We study the statistical properties of hydrophobic/polar model sequences with unique native states on the square lattice. It is shown that this ensemble of sequences differs from random sequences in significant ways in terms of both the distribution of hydrophobicity along the chains and total hydrophobicity. Whenever statistically feasible, the analogous calculations are performed for a set of real enzymes, too.

Original languageEnglish
Pages (from-to)2252-8
Number of pages7
JournalBiophysical Journal
Volume79
Issue number5
DOIs
Publication statusPublished - 2000 Nov

Keywords

  • Biophysical Phenomena
  • Biophysics
  • Enzymes
  • Models, Chemical
  • Protein Folding
  • Proteins

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