Optical coherence tomography in clinical examination of non-pigmented skin malignancies

LK Jensen, L Thrane, PE Andersen, A Tycho, F Pedersen, Stefan Andersson-Engels, N Bendsoe, Sune Svanberg, Katarina Svanberg

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

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Abstract

Optical coherence tomography (OCT) images of basal cell carcinomas (BCCs) have been acquired using a compact handheld probe with an integrated video camera allowing the OCT images to be correlated to a skin surface image. In general the healthy tissue of the skin has an obvious stratified structure, whereas the cancerous tissue shows a more homogenous structure. Thus it was demonstrated that it is possible to distinguish BCCs from healthy tissue by means of OCT. Furthermore different histological types of BCC were identified. Comparison of OCT images taken prior to and immediately after photodynamic therapy clearly shows the tissue response to the treatment, and indicates local oedema in the treated area.
Original languageEnglish
Title of host publicationOPTICAL COHERENCE TOMOGRAPHY AND COHERENCE TECHNIQUES
EditorsW Drexler
PublisherSPIE
Pages160-167
Volume5140
ISBN (Print)0-8194-5010-3
DOIs
Publication statusPublished - 2003
EventOptical Coherence Tomography and Coherence Techniques Conference, MUNICH, GERMANY, JUN 22-24, 2003 -
Duration: 0001 Jan 2 → …

Publication series

Name
Volume5140
ISSN (Print)1996-756X
ISSN (Electronic)0277-786X

Conference

ConferenceOptical Coherence Tomography and Coherence Techniques Conference, MUNICH, GERMANY, JUN 22-24, 2003
Period0001/01/02 → …

Subject classification (UKÄ)

  • Atom and Molecular Physics and Optics

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