Oxaspirodion, a new inhibitor of inducible TNF-alpha expression from the ascomycete Chaetomium subspirale

J Rether, G Erkel, T Anke, Olov Sterner

Research output: Contribution to journalArticlepeer-review

Abstract

In a search for new inhibitors of the TNF-alpha promoter activity, a new spiro-compound, designated oxaspirodion, was obtained as a mixture of four isomers from fermentations of the ascomycete Chaetomium subspirale. The structure was determined by a combination of spectroscopic techniques.
Original languageEnglish
Pages (from-to)493-495
JournalJournal of Antibiotics
Volume57
Issue number8
Publication statusPublished - 2004

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)

Subject classification (UKÄ)

  • Organic Chemistry

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