Abstract
In this issue of Blood, Matsumoto et al report that T cell-specific deletion of the cyclin-dependent kinase inhibitor p57Kip2(p57) in mice leads to a block in T-cell development as a result of hyperactivation of the E2F-p53 pathway and demonstrate that the loss of p57 accelerates lymphomagenesis in the absence of p53.
Original language | English |
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Pages (from-to) | 3370-3371 |
Journal | Blood |
Volume | 123 |
Issue number | 22 |
DOIs | |
Publication status | Published - 2014 May 29 |
Externally published | Yes |