Parkinsons sjukdom – heterogen och komplex i sitt kliniska uttryck - Individuella kombinationer av symtom som ändrar sig över tid kräver behandlingsjusteringar och anpassningar

Translated title of the contribution: Parkinson's disease - heterogeneous and complex in its clinical presentation

Filip Bergquist, Anders Johansson, Nil Dizdar, Håkan Widner, Dag Nyholm, Per Odin, Per Svenningsson

Research output: Contribution to journalArticlepeer-review


Parkinson's disease is the second most common neurodegenerative disease. Lewy bodies with alpha-synuclein as the major component and loss of dopaminergic nerve cells in substantia nigra are neuropathological features. The diagnosis of Parkinson's disease is based on the occurrence of bradykinesia, rigidity and resting tremor. The disease is also associated with several non-motor symptoms. The therapy is mainly based on pharmacological treatment to increase dopamine signaling and neurosurgical deep brain stimulation. The symptoms and signs of the progressive disease change over time, requiring treatment adjustments. Patients should be followed by a physician, nurse and a multidisciplinary team with expertise in Parkinson's disease.

Translated title of the contributionParkinson's disease - heterogeneous and complex in its clinical presentation
Original languageSwedish
Article numberFWED
Publication statusPublished - 2020 Mar 9

Subject classification (UKÄ)

  • Neurology


Dive into the research topics of 'Parkinson's disease - heterogeneous and complex in its clinical presentation'. Together they form a unique fingerprint.

Cite this