Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.

Magnus Bruze; Marléne Isaksson; Birgitta Gruvberger; Klaus E Andersen; Margarida Gonçalo; An Goossens; Jeanne D Johansen; Howard I Maibach; Thomas Rustemeyer; Christophe-J Le Coz; Ian R White

doi:10.1111/cod.12241

Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.

Magnus Bruze, Marléne Isaksson, Birgitta Gruvberger, Klaus E Andersen, Margarida Gonçalo, An Goossens, Jeanne D Johansen, Howard I Maibach, Thomas Rustemeyer, Christophe-J Le Coz, Ian R White

Research output: Contribution to journal › Article › peer-review

Abstract

Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.

Original language	English
Pages (from-to)	31-34
Journal	Contact Dermatitis
Volume	71
Issue number	1
DOIs	https://doi.org/10.1111/cod.12241
Publication status	Published - 2014

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Occupational and Environmental Dermatology Unit (013241310), Pediatrics/Urology/Gynecology/Endocrinology (013240400)

Subject classification (UKÄ)

Dermatology and Venereal Diseases

Access to Document

10.1111/cod.12241

http://www.ncbi.nlm.nih.gov/pubmed/24712418?dopt=Abstract

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Bruze, M., Isaksson, M., Gruvberger, B., Andersen, K. E., Gonçalo, M., Goossens, A., Johansen, J. D., Maibach, H. I., Rustemeyer, T., Le Coz, C.-J., & White, I. R. (2014). Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group. Contact Dermatitis, 71(1), 31-34. https://doi.org/10.1111/cod.12241

@article{9dd4771f0b224f5b9a97c869d629ffb7,

title = "Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.",

abstract = "Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG({\textregistered}) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.",

author = "Magnus Bruze and Marl{\'e}ne Isaksson and Birgitta Gruvberger and Andersen, {Klaus E} and Margarida Gon{\c c}alo and An Goossens and Johansen, {Jeanne D} and Maibach, {Howard I} and Thomas Rustemeyer and {Le Coz}, Christophe-J and White, {Ian R}",

note = "The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Occupational and Environmental Dermatology Unit (013241310), Pediatrics/Urology/Gynecology/Endocrinology (013240400)",

year = "2014",

doi = "10.1111/cod.12241",

language = "English",

volume = "71",

pages = "31--34",

journal = "Contact Dermatitis",

issn = "0105-1873",

publisher = "Wiley-Blackwell",

number = "1",

}

Bruze, M , Isaksson, M, Gruvberger, B, Andersen, KE, Gonçalo, M, Goossens, A, Johansen, JD, Maibach, HI, Rustemeyer, T, Le Coz, C-J & White, IR 2014, 'Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.', Contact Dermatitis, vol. 71, no. 1, pp. 31-34. https://doi.org/10.1111/cod.12241

Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group. / Bruze, Magnus ; Isaksson, Marléne; Gruvberger, Birgitta et al.
In: Contact Dermatitis, Vol. 71, No. 1, 2014, p. 31-34.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Patch testing with methylchloroisothiazolinone/methylisothiazolinone 200 ppm aq. detects significantly more contact allergy than 100 ppm. A multicentre study within the European Environmental and Contact Dermatitis Research Group.

AU - Bruze, Magnus

AU - Isaksson, Marléne

AU - Gruvberger, Birgitta

AU - Andersen, Klaus E

AU - Gonçalo, Margarida

AU - Goossens, An

AU - Johansen, Jeanne D

AU - Maibach, Howard I

AU - Rustemeyer, Thomas

AU - Le Coz, Christophe-J

AU - White, Ian R

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Occupational and Environmental Dermatology Unit (013241310), Pediatrics/Urology/Gynecology/Endocrinology (013240400)

PY - 2014

Y1 - 2014

N2 - Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.

AB - Methylchloroisothiazolinone (MCI) and methylisothiazolinone (MI) are the active ingredients in commonly used preservative systems (e.g. Kathon CG(®) ). MCI/MI is present in the European baseline patch test series at 100 ppm aq. Since 1986, 200 ppm (dose 0.006 mg/cm(2) ) has been used in Sweden without causing skin irritation. Centres in Spain, the United Kingdom and Ireland have also used 200 ppm in their baseline series.

U2 - 10.1111/cod.12241

DO - 10.1111/cod.12241

M3 - Article

C2 - 24712418

SN - 0105-1873

VL - 71

SP - 31

EP - 34

JO - Contact Dermatitis

JF - Contact Dermatitis

IS - 1

ER -