Pathogenic Mechanisms in Lupus Nephritis: Nucleosomes Bind Aberrant Laminin β1 With High Affinity and Colocalize in the Electron-Dense Deposits.

Anders Olin; Matthias Mörgelin; Lennart Truedsson; Gunnar Sturfelt; Anders Bengtsson

doi:10.1002/art.38250

Pathogenic Mechanisms in Lupus Nephritis: Nucleosomes Bind Aberrant Laminin β1 With High Affinity and Colocalize in the Electron-Dense Deposits.

Anders Olin, Matthias Mörgelin, Lennart Truedsson, Gunnar Sturfelt, Anders Bengtsson

Research output: Contribution to journal › Article › peer-review

24 Citations (SciVal)

Abstract

Apoptotic nucleosomes are structurally and immunologically involved in lupus nephritis. The purpose of this study was to examine the expression and function of laminins and their interactions with nucleosomes in the kidneys of patients with lupus nephritis, using surface plasmon resonance (SPR) analysis.

Original language	English
Pages (from-to)	397-406
Journal	Arthritis & Rheumatology
Volume	66
Issue number	2
DOIs	https://doi.org/10.1002/art.38250
Publication status	Published - 2014

Subject classification (UKÄ)

Rheumatology and Autoimmunity

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10.1002/art.38250

http://www.ncbi.nlm.nih.gov/pubmed/24504812?dopt=Abstract

Cite this

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title = "Pathogenic Mechanisms in Lupus Nephritis: Nucleosomes Bind Aberrant Laminin β1 With High Affinity and Colocalize in the Electron-Dense Deposits.",

abstract = "Apoptotic nucleosomes are structurally and immunologically involved in lupus nephritis. The purpose of this study was to examine the expression and function of laminins and their interactions with nucleosomes in the kidneys of patients with lupus nephritis, using surface plasmon resonance (SPR) analysis.",

author = "Anders Olin and Matthias M{\"o}rgelin and Lennart Truedsson and Gunnar Sturfelt and Anders Bengtsson",

year = "2014",

doi = "10.1002/art.38250",

language = "English",

volume = "66",

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journal = "Arthritis & Rheumatology",

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publisher = "John Wiley & Sons Inc.",

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Pathogenic Mechanisms in Lupus Nephritis: Nucleosomes Bind Aberrant Laminin β1 With High Affinity and Colocalize in the Electron-Dense Deposits. / Olin, Anders; Mörgelin, Matthias; Truedsson, Lennart; Sturfelt, Gunnar; Bengtsson, Anders.

In: Arthritis & Rheumatology, Vol. 66, No. 2, 2014, p. 397-406.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Pathogenic Mechanisms in Lupus Nephritis: Nucleosomes Bind Aberrant Laminin β1 With High Affinity and Colocalize in the Electron-Dense Deposits.

AU - Olin, Anders

AU - Mörgelin, Matthias

AU - Truedsson, Lennart

AU - Sturfelt, Gunnar

AU - Bengtsson, Anders

PY - 2014

Y1 - 2014

N2 - Apoptotic nucleosomes are structurally and immunologically involved in lupus nephritis. The purpose of this study was to examine the expression and function of laminins and their interactions with nucleosomes in the kidneys of patients with lupus nephritis, using surface plasmon resonance (SPR) analysis.

AB - Apoptotic nucleosomes are structurally and immunologically involved in lupus nephritis. The purpose of this study was to examine the expression and function of laminins and their interactions with nucleosomes in the kidneys of patients with lupus nephritis, using surface plasmon resonance (SPR) analysis.

U2 - 10.1002/art.38250

DO - 10.1002/art.38250

M3 - Article

C2 - 24504812

VL - 66

SP - 397

EP - 406

JO - Arthritis & Rheumatology

JF - Arthritis & Rheumatology

SN - 2326-5205

IS - 2

ER -

Pathogenic Mechanisms in Lupus Nephritis: Nucleosomes Bind Aberrant Laminin β1 With High Affinity and Colocalize in the Electron-Dense Deposits.

Abstract

Subject classification (UKÄ)

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