Pathogenic Mechanisms in Lupus Nephritis: Nucleosomes Bind Aberrant Laminin β1 With High Affinity and Colocalize in the Electron-Dense Deposits.

Anders Olin, Matthias Mörgelin, Lennart Truedsson, Gunnar Sturfelt, Anders Bengtsson

Research output: Contribution to journalArticlepeer-review

24 Citations (SciVal)

Abstract

Apoptotic nucleosomes are structurally and immunologically involved in lupus nephritis. The purpose of this study was to examine the expression and function of laminins and their interactions with nucleosomes in the kidneys of patients with lupus nephritis, using surface plasmon resonance (SPR) analysis.
Original languageEnglish
Pages (from-to)397-406
JournalArthritis & Rheumatology
Volume66
Issue number2
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Rheumatology and Autoimmunity

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