Perdeuteration of Biological Macromolecules: A Case Study of Human Carbonic Anhydrases

Katarina Koruza

Research output: Thesis › Doctoral Thesis (compilation)

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4 Article

4 results

2019
Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative
Koruza, K., Mahon, B. P., Blakeley, M. P., Ostermann, A., Schrader, T. E., McKenna, R., Knecht, W. & Fisher, S. Z., 2019, In: Journal of Structural Biology. 205, 2, p. 147-154
Research output: Contribution to journal › Article › peer-review
2018
From initial hit to crystal optimization with microseeding of human carbonic anhydrase IX—A case study for neutron protein crystallography
Koruza, K., Lafumat, B., Nyblom, M., Knecht, W. & Fisher, Z., 2018 Nov 9, In: Crystals. 8, 11, 434.
Research output: Contribution to journal › Article › peer-review

Open Access
Deuteration of human carbonic anhydrase for neutron crystallography: Cell culture media, protein thermostability, and crystallization behavior
Koruza, K., Lafumat, B., Végvári, Knecht, W. & Fisher, S. Z., 2018 May 1, In: Archives of Biochemistry and Biophysics. 645, p. 26-33 8 p.
Research output: Contribution to journal › Article › peer-review
2017
Improved molecular recognition of Carbonic Anhydrase IX by polypeptide conjugation to acetazolamide
Yang, J., Koruza, K., Fisher, Z., Knecht, W. & Baltzer, L., 2017 Oct, In: Bioorganic and Medicinal Chemistry. 25, 20, p. 5838-5848
Research output: Contribution to journal › Article › peer-review