Performing Enriched Environment Studies to Improve Functional Recovery

Daniela Talhada, Karsten Ruscher

Research output: Contribution to journalArticlepeer-review

Abstract

Physical therapy and social interactions between the stroke patient and healthcare professionals or relatives facilitate the process of recovery and promote improvement of lost neurological function after stroke. These observations can be mimicked in an experimental setting by multimodal stimulation provided in the concept of enriched environment. The enriched environment is a housing condition combining social interactions and sensorimotor stimulation that improves lost neurological function without affecting the extent of brain damage after experimental stroke. This chapter provides a detailed protocol on how to perform enriched housing experiments including conceptual and technical considerations as a tool to investigate mechanisms of recovery after brain injury.

Original languageEnglish
Pages (from-to)355-366
Number of pages12
JournalMethods in molecular biology (Clifton, N.J.)
Volume2616
DOIs
Publication statusPublished - 2023

Subject classification (UKÄ)

  • Neurology

Free keywords

  • Behavior
  • Cell genesis
  • Enriched environment
  • Functional recovery
  • Glial scar
  • Mouse
  • Plasticity
  • Rat
  • Rehabilitation
  • Remodeling
  • Rodents
  • Rotating pole test

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