Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy.

Mattias Levin; Jasmine J King; Jacob Glanville; Katherine J L Jackson; Timothy J Looney; Ramona A Hoh; Adriano Mari; Morgan Andersson; Lennart Greiff; Andrew Z Fire; Scott D Boyd; Mats Ohlin

doi:10.1016/j.jaci.2015.09.027

Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy.

Mattias Levin, Jasmine J King, Jacob Glanville, Katherine J L Jackson, Timothy J Looney, Ramona A Hoh, Adriano Mari, Morgan Andersson, Lennart Greiff, Andrew Z Fire, Scott D Boyd, Mats Ohlin

Research output: Contribution to journal › Article › peer-review

Abstract

Specific immunotherapy (SIT) is the only treatment with proved long-term curative potential in patients with allergic disease. Allergen-specific IgE is the causative agent of allergic disease, and antibodies contribute to SIT, but the effects of SIT on aeroallergen-specific B-cell repertoires are not well understood.

Original language	English
Pages (from-to)	1535-1544
Journal	The Journal of Allergy and Clinical Immunology
Volume	137
Issue number	5
Early online date	2015 Nov 7
DOIs	https://doi.org/10.1016/j.jaci.2015.09.027
Publication status	Published - 2016

Subject classification (UKÄ)

Respiratory Medicine and Allergy

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10.1016/j.jaci.2015.09.027

http://www.ncbi.nlm.nih.gov/pubmed/26559321?dopt=Abstract

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Levin, M., King, J. J., Glanville, J., Jackson, K. J. L., Looney, T. J., Hoh, R. A., Mari, A., Andersson, M., Greiff, L., Fire, A. Z., Boyd, S. D., & Ohlin, M. (2016). Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy. The Journal of Allergy and Clinical Immunology, 137(5), 1535-1544. https://doi.org/10.1016/j.jaci.2015.09.027

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title = "Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy.",

abstract = "Specific immunotherapy (SIT) is the only treatment with proved long-term curative potential in patients with allergic disease. Allergen-specific IgE is the causative agent of allergic disease, and antibodies contribute to SIT, but the effects of SIT on aeroallergen-specific B-cell repertoires are not well understood.",

author = "Mattias Levin and King, {Jasmine J} and Jacob Glanville and Jackson, {Katherine J L} and Looney, {Timothy J} and Hoh, {Ramona A} and Adriano Mari and Morgan Andersson and Lennart Greiff and Fire, {Andrew Z} and Boyd, {Scott D} and Mats Ohlin",

year = "2016",

doi = "10.1016/j.jaci.2015.09.027",

language = "English",

volume = "137",

pages = "1535--1544",

journal = "Journal of Allergy and Clinical Immunology",

issn = "1097-6825",

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}

Levin, M, King, JJ, Glanville, J, Jackson, KJL, Looney, TJ, Hoh, RA, Mari, A, Andersson, M, Greiff, L, Fire, AZ, Boyd, SD & Ohlin, M 2016, 'Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy.', The Journal of Allergy and Clinical Immunology, vol. 137, no. 5, pp. 1535-1544. https://doi.org/10.1016/j.jaci.2015.09.027

TY - JOUR

T1 - Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy.

AU - Levin, Mattias

AU - King, Jasmine J

AU - Glanville, Jacob

AU - Jackson, Katherine J L

AU - Looney, Timothy J

AU - Hoh, Ramona A

AU - Mari, Adriano

AU - Andersson, Morgan

AU - Greiff, Lennart

AU - Fire, Andrew Z

AU - Boyd, Scott D

AU - Ohlin, Mats

PY - 2016

Y1 - 2016

N2 - Specific immunotherapy (SIT) is the only treatment with proved long-term curative potential in patients with allergic disease. Allergen-specific IgE is the causative agent of allergic disease, and antibodies contribute to SIT, but the effects of SIT on aeroallergen-specific B-cell repertoires are not well understood.

AB - Specific immunotherapy (SIT) is the only treatment with proved long-term curative potential in patients with allergic disease. Allergen-specific IgE is the causative agent of allergic disease, and antibodies contribute to SIT, but the effects of SIT on aeroallergen-specific B-cell repertoires are not well understood.

U2 - 10.1016/j.jaci.2015.09.027

DO - 10.1016/j.jaci.2015.09.027

M3 - Article

C2 - 26559321

VL - 137

SP - 1535

EP - 1544

JO - Journal of Allergy and Clinical Immunology

JF - Journal of Allergy and Clinical Immunology

SN - 1097-6825

IS - 5

ER -

Persistence and evolution of allergen-specific IgE repertoires during subcutaneous specific immunotherapy.

Abstract

Subject classification (UKÄ)

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