Personalizing pancreatic cancer medicine: what are the challenges?

Krissi Danielsson, Daniel Ansari, Roland Andersson

Research output: Contribution to journalReview articlepeer-review

Abstract

The P4 paradigm for future medicine promises changes in cancer management with improved Prediction of treatment response, Prevention of disease, Personalization of therapy, and Participation by patients. Significant challenges remain for the implementation of the P4 principles for pancreatic cancer, but many strides have been made in the past several years that should facilitate a future in which the disease can be detected at earlier stages and treatments can be customized to target features of a particular patient's disease. This article summarizes the basic molecular biology of pancreatic tumors and the current state of pancreatic cancer treatment, as well as targeted treatments in the pipeline that might enable future personalized pancreatic cancer treatment and prediction of response to treatment. It also discusses possible directions for screening patients at high risk of developing the disease, detecting tumors at earlier stages, and increasing patient involvement in designing treatment.
Original languageEnglish
Pages (from-to)45-59
JournalPersonalized Medicine
Volume10
Issue number1
DOIs
Publication statusPublished - 2013

Subject classification (UKÄ)

  • Surgery

Free keywords

  • biomarkers
  • P4
  • pancreatic cancer
  • personalized medicine

Fingerprint

Dive into the research topics of 'Personalizing pancreatic cancer medicine: what are the challenges?'. Together they form a unique fingerprint.

Cite this