Phase Behavior and Coassembly of DNA and Lysozyme in Dilute Aqueous Mixtures: A Model Investigation of DNA-Protein Interactions

Dan Lundberg; Anna Carnerup; Karin Schillén; Maria da Graca Miguel; Björn Lindman

doi:10.1021/la904104w

Phase Behavior and Coassembly of DNA and Lysozyme in Dilute Aqueous Mixtures: A Model Investigation of DNA-Protein Interactions

Dan Lundberg, Anna Carnerup, Karin Schillén, Maria da Graca Miguel, Björn Lindman

Physical Chemistry

Research output: Contribution to journal › Letter › peer-review

Abstract

Results from an experimental investigation of the phase behavior of an aqueous system of DNA from salmon testes and the protein lysozyme arc presented. At very low concentrations of either or both of the macromolecular components, wormlike assemblies with a width of the order of 10 nm are formed. There are strong indications that direct interactions between the protein units are instrumental both in driving the phase separation and in controlling the morphology of the formed assemblies.

Original language	English
Pages (from-to)	2986-2988
Journal	Langmuir
Volume	26
Issue number	5
DOIs	https://doi.org/10.1021/la904104w
Publication status	Published - 2010

Subject classification (UKÄ)

Physical Chemistry

Access to Document

10.1021/la904104w

Cite this

@article{510a7daea0d14fc990df2c880bfeb3ac,

title = "Phase Behavior and Coassembly of DNA and Lysozyme in Dilute Aqueous Mixtures: A Model Investigation of DNA-Protein Interactions",

abstract = "Results from an experimental investigation of the phase behavior of an aqueous system of DNA from salmon testes and the protein lysozyme arc presented. At very low concentrations of either or both of the macromolecular components, wormlike assemblies with a width of the order of 10 nm are formed. There are strong indications that direct interactions between the protein units are instrumental both in driving the phase separation and in controlling the morphology of the formed assemblies.",

author = "Dan Lundberg and Anna Carnerup and Karin Schill{\'e}n and Miguel, {Maria da Graca} and Bj{\"o}rn Lindman",

year = "2010",

doi = "10.1021/la904104w",

language = "English",

volume = "26",

pages = "2986--2988",

journal = "Langmuir",

issn = "0743-7463",

publisher = "The American Chemical Society (ACS)",

number = "5",

}

TY - JOUR

T1 - Phase Behavior and Coassembly of DNA and Lysozyme in Dilute Aqueous Mixtures: A Model Investigation of DNA-Protein Interactions

AU - Lundberg, Dan

AU - Carnerup, Anna

AU - Schillén, Karin

AU - Miguel, Maria da Graca

AU - Lindman, Björn

PY - 2010

Y1 - 2010

N2 - Results from an experimental investigation of the phase behavior of an aqueous system of DNA from salmon testes and the protein lysozyme arc presented. At very low concentrations of either or both of the macromolecular components, wormlike assemblies with a width of the order of 10 nm are formed. There are strong indications that direct interactions between the protein units are instrumental both in driving the phase separation and in controlling the morphology of the formed assemblies.

AB - Results from an experimental investigation of the phase behavior of an aqueous system of DNA from salmon testes and the protein lysozyme arc presented. At very low concentrations of either or both of the macromolecular components, wormlike assemblies with a width of the order of 10 nm are formed. There are strong indications that direct interactions between the protein units are instrumental both in driving the phase separation and in controlling the morphology of the formed assemblies.

U2 - 10.1021/la904104w

DO - 10.1021/la904104w

M3 - Letter

C2 - 20121070

SN - 0743-7463

VL - 26

SP - 2986

EP - 2988

JO - Langmuir

JF - Langmuir

IS - 5

ER -

Phase Behavior and Coassembly of DNA and Lysozyme in Dilute Aqueous Mixtures: A Model Investigation of DNA-Protein Interactions

Abstract

Subject classification (UKÄ)

Access to Document

Fingerprint

Cite this