Plasma homocysteine in 80-year-olds Relationships to medical, psychological and social variables.

E Jensen, Ove Dehlin, Eva Marie Erfurth, Bo Hagberg, Gillis Samuelsson, Torbjörn Svensson, Björn Hultberg

Research output: Contribution to journalArticlepeer-review

Abstract

Plasma homocysteine concentrations in a group of 80-year-old persons were related to symptoms and signs. Plasma homocysteine concentrations higher than 15 mumol/l were associated with lower total life satisfaction (P<0.01), mood (P<0.05), zest for life (P<0.05), lower scores for reasoning (P<0.05), spatial ability (P<0.05), memory recognition (P<0.05), and subjective health (P<0.01). In an instrument comprising of 30 symptoms, plasma homocysteine concentrations higher than 15 mumol/l were associated with impaired concentration (P<0.05), restlessness (P<0.05), feeling cold (P<0.05), loss of weight (P<0.05), and feeling depressed (P<0.01). The above data indicate that plasma homocysteine values over 15 mumol/l could be relevant markers for clinical intervention.
Original languageEnglish
Pages (from-to)215-226
JournalArchives of Gerontology and Geriatrics
Volume26
Issue number3
DOIs
Publication statusPublished - 1998

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Division of Clinical Chemistry and Pharmacology (013250300), Division of Geriatric Medicine (013040040), Division of Occupational Therapy (Closed 2012) (013025000), Medicine (Lund) (013230025), Department of Psychology (012010000)

Subject classification (UKÄ)

  • Gerontology, specializing in Medical and Health Sciences

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