Plasma levels of galectin-3-binding protein reflect type I interferon activity and are increased in patients with systemic lupus erythematosus.

Christoffer T Nielsen, Christian Lood, Ole Ostergaard, Line V Iversen, Anne Voss, Anders Bengtsson, Søren Jacobsen, Niels H H Heegaard

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Abstract

Simple measures of type I interferon (IFN) activity constitute highly attractive biomarkers in systemic lupus erythematosus (SLE). We explore galectin-3-binding protein (G3BP) as a novel measure of type I IFN activity and serum/plasma biomarker in large independent cohorts of patients with SLE and controls.
Original languageEnglish
Pages (from-to)e000026
JournalLupus science & medicine
Volume1
Issue number1
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Rheumatology and Autoimmunity

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