Abstract
The crude MeOH extract prepared from the aerial parts of G. stepporum and its EtOAc, n-BuOH, H2O subextracts were screened for their inhibitory activity on H2O2-induced lipid peroxidation in human red blood cells. The EtOAc subextract was found to be the most active one and its chemical composition was further analysed. Six polyphenolic secondary metabolites including quercetin (1), rutin (2), methyl gallate (3), pusilagin (4), 1,3,6-tri-O-galloyl-beta-glucospyranose (5) and 1,2,3,4,6-penta-O-galloyl-beta-glucopyranose (6) were isolated from the EtOAc extract by successive chromatographic methods (Sephadex CC, silica gel CC and P-TLC). The structures of the isolates were elucidated by 1D- and 2D-NMR and MS. This is the first report of occurrence of hydrolysable tannins in G. stepporum.
| Original language | English |
|---|---|
| Pages (from-to) | 22-28 |
| Journal | Records of Natural Products |
| Volume | 5 |
| Issue number | 1 |
| Publication status | Published - 2011 |
Bibliographical note
The information about affiliations in this record was updated in December 2015.The record was previously connected to the following departments: Organic chemistry (S/LTH) (011001240)
Subject classification (UKÄ)
- Organic Chemistry
Keywords
- Geranium stepporum
- Geraniaceae
- galloylglucopyranose
- hydrolysable
- tannin
- flavonoid
- antioxidant effect