Prior information in fluorescence molecular tomography based on multispectral fluorescence emission

Johan Axelsson, Jenny Svensson, Stefan Andersson-Engels

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

199 Downloads (Pure)

Abstract

Fluorescence molecular tomography (FMT) suffers from inherent ill-posedness due to the vast number of possible solutions to the reconstruction problem. To increase the robustness of such a problem one need prior information. We present here a method for rendering a priori information of the position of a fluorescent inclusion inside turbid media. The method utilizes solely two spectral bands within the fluorescence spectrum emitted from the fluorophore. The method is presented and verified using experimental data from a tissue phantom. The confinement is also used to impose weights onto the voxels before the inversion of the linear set of equations describing the FMT problem.
Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
PublisherSPIE
PagesD4340-D4340
Volume6434
ISBN (Print)9780819465474
DOIs
Publication statusPublished - 2007
EventOptical Tomography and Spectroscopy of Tissue VII - San Jose, CA, United States
Duration: 2007 Jan 212007 Jan 24

Publication series

Name
Volume6434
ISSN (Print)1605-7422
ISSN (Electronic)1042-4687

Conference

ConferenceOptical Tomography and Spectroscopy of Tissue VII
Country/TerritoryUnited States
CitySan Jose, CA
Period2007/01/212007/01/24

Subject classification (UKÄ)

  • Atom and Molecular Physics and Optics

Free keywords

  • Fluorescence molecular tomography
  • Priori information
  • Turbid media
  • Reconstruction schemes

Fingerprint

Dive into the research topics of 'Prior information in fluorescence molecular tomography based on multispectral fluorescence emission'. Together they form a unique fingerprint.

Cite this