Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review

Fadi N. Salloum, Carlo G. Tocchetti, Pietro Ameri, Hossein Ardehali, Aarti Asnani, Rudolf A. de Boer, Paul Burridge, José Ángel Cabrera, Javier de Castro, Raúl Córdoba, Ambra Costa, Susan Dent, Daniel Engelbertsen, María Fernández-Velasco, Mike Fradley, José J. Fuster, Carlos Galán-Arriola, Inés García-Lunar, Alessandra Ghigo, Anna González-NeiraEmilio Hirsch, Borja Ibáñez, Rickard N. Kitsis, Suma Konety, Alexander R. Lyon, Pilar Martin, Adolfo G. Mauro, Manuel M. Mazo Vega, Wouter C. Meijers, Tomas G. Neilan, Tienush Rassaf, Melanie Ricke-Hoch, Pilar Sepulveda, Paaladinesh Thavendiranathan, Peter van der Meer, Valentin Fuster, Bonnie Ky, Teresa López-Fernández, International Cardio-Oncology Society

Research output: Contribution to journalReview articlepeer-review

Abstract

Despite improvements in cancer survival, cancer therapy–related cardiovascular toxicity has risen to become a prominent clinical challenge. This has led to the growth of the burgeoning field of cardio-oncology, which aims to advance the cardiovascular health of cancer patients and survivors, through actionable and translatable science. In these Global Cardio-Oncology Symposium 2023 scientific symposium proceedings, we present a focused review on the mechanisms that contribute to common cardiovascular toxicities discussed at this meeting, the ongoing international collaborative efforts to improve patient outcomes, and the bidirectional challenges of translating basic research to clinical care. We acknowledge that there are many additional therapies that are of significance but were not topics of discussion at this symposium. We hope that through this symposium-based review we can highlight the knowledge gaps and clinical priorities to inform the design of future studies that aim to prevent and mitigate cardiovascular disease in cancer patients and survivors.

Original languageEnglish
Pages (from-to)715-731
JournalJACC: CardioOncology
Volume5
Issue number6
DOIs
Publication statusPublished - 2023

Subject classification (UKÄ)

  • Cardiac and Cardiovascular Systems

Free keywords

  • anthracyclines
  • basic research
  • cancer
  • cardiac arrhythmias
  • cardio-oncology
  • cardiotoxicity
  • chemotherapy
  • immunotherapy
  • translational research

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